Published Data Registry

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Versatile Microfluidics Platform for Enhanced Multitarget Super-Resolution Microscopy (Open Access) Basak S, Vu K, (...), Tsukanov R ACS Nano 2026
Membrane-protein-mediated phase separation orchestrates organelle contact sites (Open Access) Hoffmann C, Nagao T, (...), Milovanovic D Molecular Cell 2026
Cracks in the Foundation: How Data-Hungry and Sensitive to Domain Shift are Vision Foundation Models for Computational Pathology? (Open Access) Witte A, Fuhlert P, (...), Bonn S medRxiv 2026
Push-and-pull protein dynamics leads to log-normal synaptic sizes and probabilistic multi-spine plasticity (Open Access) Petkovic J, Eggl MF, (...), Tchumatchenko T bioRxiv 2026
Munc13-1 couples DAG and Ca2+ signaling to dynamic vesicle priming, synaptic short-term plasticity, and posttetanic potentiation (Open Access) Ranjan M, Lin K, (...), Taschenberger H Science Advances 2026
Encephalopathy-linked UFM1 variants impede neuronal protein translation, development, and function (Open Access) Perdigão C, Torres J, (...), Tirard M EMBO Molecular Medicine 2026
Dendritic heterosynaptic plasticity arises from calcium-based input learning (Open Access) Shafiee S, Schmitt S, Tetzlaff C Communications Biology 2026
On the power and limits of foundation model image embeddings for privacy-preserving federated learning (Open Access) Lohmann J, Witte A, (...), Baumbach J Array 2026
Structure and polydispersity of single lipid vesicles by small-angle X-ray scattering at European XFEL (Open Access) Neuhaus C, Stammer ML, (...), Salditt T Communications Physics 2026
Nanobodies equipped with HaloTag variants enable rapid and straightforward one-step immunofluorescence lifetime multiplexing (Open Access) Albert L, Basak S, (...), Opazo F bioRxiv 2026
Dynamin optimizes protein-membrane interactions for fission (Open Access) Spencer RKW, Müller M npj Soft Matter 2026
Vesicle dynamics in synapsin-induced condensates by passive X-ray microrheology (Open Access) Czajka T, Major A, (...), Salditt T Biophysical Journal 2026
Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease (Open Access) Pradhan R, Petrovic Z, (...), Fischer A Advanced Science 2026
A correlative workflow for synaptic imaging by cryo-electron tomography (Open Access) Do TT, Siegert A, (...), Fernández-Busnadiego R Structure 2026
Neuroinflammatory profiles and cellular localization of TNF-α associated with chronic vanadium neurotoxicity Folarin R, Olopade F, (...), Olopade JO Metabolic Brain Disease 2026
Post‐transcriptional regulatory networks: The dynamic interplay of RNA‐binding proteins (Open Access) Street LA, Jovanovic M, Fornasiero EF FEBS Journal 2026
In‐situ‐Konstruktion von Imidazopyridinium‐Fluoreszenzlabels für Biokonjugationen (Open Access) Du D, Albert L, (...), Simeth NA Angewandte Chemie 2026
In Situ Construction of Imidazopyridinium Fluorescent Labels for Bioconjugation (Open Access) Du D, Albert L, (...), Simeth NA Angewandte Chemie-International Edition 2026
Selective, genetically induced increase in synaptic vesicle priming (Open Access) Aldahabi M, Balint F, Lorincz A, Lipstein N, Brose N, Nusser Z Science Advances 2026
Brain Alterations Linked to the MPTP Mouse Model of Parkinson's Disease Uncovered by Diffusion Kurtosis Imaging and Magnetic Resonance Spectroscopy (Open Access) Modi A, Maria S, (...), Khairnar A CNS Neuroscience & Therapeutics 2026
The epitranscriptomic m6A RNA modification modulates the synapse in ageing and in a mouse model of synucleinopathy (Open Access) Chopra A, Xylaki M, (...), Outeiro TF npj Parkinsons Disease 2026
A versatile nanobody platform for live and super-resolution imaging of synaptic vesicle dynamics and plasticity in rodent and human neurons (Open Access) Goel R, Jevdokimenko K, (...), Fornasiero EF Journal of Nanobiotechnology 2026
Encoding performance of cortical neurons critically depends on their morphological and neurophysiological properties (Open Access) Revah O, Wolf F, Gutnick MJ, Neef A PLOS Biology 2026
Lewy Bodies Are Not Associated With Neuronal or Synaptic Loss in Dementia With Lewy Bodies (Open Access) Hawksworth JI, Kirkby‐Geddes E, (...), Erskine D Neuropathology and Applied Neurobiology 2026
Artificial Intelligence for Discovery in Life Sciences (Open Access) Chanda S, Rizzoli SO, Shaib AH Bioconjugate Chemistry 2026
Plastic Arbor: A modern simulation framework for synaptic plasticity—From single synapses to networks of morphological neurons (Open Access) Luboeinski J, Schmitt S, Shafiee S, Hater T, Bösch F, Tetzlaff C PLOS Computational Biology 2026
Caging-group-free photoactivatable fluorophores with far-red emission (Open Access) Lincoln R, Butkevich AN, (...), Hell SW Chem 2026
Blood-derived microRNA signatures associated with hippocampal structure and atrophy rate: findings from the Rhineland Study (Open Access) Melas K, Talevi V, (...), Breteler MMB Molecular Psychiatry 2026
The lncRNA Gm16685/MITA1 modulates inflammatory astrocyte reactivity through PCBP2 associated regulation of IKKβ signaling (Open Access) Fuchs U, Schroeder S, (...), Fischer A bioRxiv 2026
Loss of the lncRNA SOX1-OT promotes p53-dependent cell-cycle arrest in astrocytes (Open Access) Fuchs U, Schröder S, (...), Fischer A bioRxiv 2026
A High-Affinity Nanobody Recognizing mNeonGreen Enables Versatile Biochemical, Cellular, and in vivo Applications (Open Access) Gere-Becker M, Funk L, (...), Frey S bioRxiv 2026
The missing link: Piccolino is essential for tethering synaptic vesicles to rod photoreceptor ribbons (Open Access) Gierke K, Gadomska M, (...), Brandstätter JH Journal of Cell Biology 2026
LRRK2/LRRK1 interactions modulate Rab7 activity and inhibit lysosomal exocytosis (Open Access) Merghani M, Gerhardt E, Hesse M, Fahlbusch C, Böcker CA, Outeiro TF bioRxiv 2026
A microfluidics platform for studying ion and solute transport by isolated synaptic vesicles (Open Access) Upmanyu N, Olsthoorn L, (...), Jahn R Colloids and Surfaces B-Biointerfaces 2026
ONE microscopy Shaib AH, Alawieh MM, Rizzoli SO Nature Protocols 2026
How (We Think) Parkinson's disease begins (Open Access) Outeiro TF, Tolosa E Parkinsonism & Related Disorders 2026
RNA Promotes Synapsin Condensates That Organize Synaptic Vesicles in Live Neurons and Enable Localized Translation in Reconstituted System (Open Access) Rankovic B, Geisterfer ZM, (...), Milovanovic D Advanced Science 2026
EXPOSE: Explainable and Domain-Robust Embeddings from Pathology Vision Foundation Models using Sparse Autoencoders (Open Access) Witte A, Lennartz M, (...), Zimmermann M arXiv 2026
Signatures of Hebbian plasticity in the nanoscale morphodynamics of cortical spines (Open Access) Soltanipour M, Nagel A, Willig KI, Wolf F bioRxiv 2026
Nanobodies Equippedwith HaloTag Enable Scalable Fluorescence-LifetimeMultiplexing (Open Access) Albert L, Basak S, (...), Opazo F ACS Nano 2026
Super-resolution microscopy of mitochondrial mRNAs (Open Access) Stoldt S, Maass F, (...), Jakobs S bioRxiv 2025
RNA promotes synapsin coacervation and modulates local translation (Open Access) Rankovic B, Geisterfer ZM, (...), Milovanovic D bioRxiv 2025
LncRNA 3222401L13Rik Is Upregulated in Aging Astrocytes and Regulates Neuronal Support Function Through Interaction with Npas3 (Open Access) Schröder S, Sakib MS, (...), Fischer A Non-Coding RNA 2025
Glutamatergic synaptic resilience to overexpressed human alpha-synuclein (Open Access) Santos PI, Garcia-Plaza IH, (...), Outeiro TF bioRxiv 2025
Protein misfolding: understanding biology to classify and treat synucleinopathies (Open Access) Outeiro TF, Höglinger G, Lang AE, Vieira TCRG Journal of Neural Transmission 2025
A novel alpha-synuclein K58N missense variant in a patient with Parkinson's disease (Open Access) Al-Azzani M, Weber S, (...), Outeiro TF medRxiv 2025
Controlling the Formation of Multiple Condensates in the Synapse (Open Access) Safari N, do Rego Barros Fernandes Lima MA, Rossetto R, Zwicker D, D’Este E, Tetzlaff C bioRxiv 2025
Caging-group-free photoactivatable fluorophores with far-red emission (Open Access) Lincoln R, Butkevich AN, (...), Hell SW bioRxiv 2025
Inhibition of the Parkinson’s Disease-Related Protein DJ-1 by Endogenous Neurotoxins of the 1,2,3,4-Tetrahydroisoquinoline Family Laurent C, Poncet G, (...), Dairou J ACS Chemical Neuroscience 2025
A correlative workflow streamlines synaptic imaging by cryo-electron tomography (Open Access) Do TT, Siegert A, (...), Fernández-Busnadiego R bioRxiv 2025
3D virtual histology of rodent and primate cochleae with multi-scale phase-contrast X-ray tomography (Open Access) Schaeper JJ, Kampshoff CA, (...), Salditt T Scientific Reports 2025
Turnover atlas of proteome and phosphoproteome across mouse tissues and brain regions (Open Access) Li W, Dasgupta A, (...), Liu Y Cell 2025
PHluorin-conjugated secondary nanobodies as a tool for measuring synaptic vesicle exocytosis and endocytosis (Open Access) Georgiev SV, Rizzoli SO Scientific Reports 2025
Number and relative abundance of synaptic vesicles in functionally distinct priming states determine synaptic strength and short‐term plasticity (Open Access) Lin K, Ranjan M, Lipstein N, Brose N, Neher E, Taschenberger H Journal of Physiology 2025
Microtubules as a versatile reference standard for expansion microscopy (Open Access) Chowdhury R, Mimoso T, (...), Shaib AH Communications Biology 2025
Understanding mitochondrial protein import: a revised model of the presequence translocase (Open Access) Jain N, Chacinska A, Rehling P Trends in Biochemical Sciences 2025
Investigation of neuromodulation of the endbulb of Held synapse in the cochlear nucleus by serotonin and norepinephrine (Open Access) Groshkova MB, Alvanos T, (...), Moser T Frontiers in Cellular Neuroscience 2025
Neuromodulation of the endbulb of Held synapse in the cochlear nucleus (Open Access) Groshkova M, Alvanos T, (...), Moser T bioRxiv 2025
Synchronization in epithelial tissue morphogenesis (Open Access) Richa P, Häring M, (...), Kong D Current Biology 2025
Investigating the Molecular Composition of Neuronal Subcompartments Using Proximity Labeling Lohse M, Sun S, (...), Lipstein N Methods in Molecular Biology 2025
Distinct transmission sites within a synapse for strengthening and homeostasis (Open Access) Yang Y, Wong MH, (...), Schlüter OM Science Advances 2025
A role for astrocytic miR-129-5p in frontotemporal dementia (Open Access) Kaurani L, Pradhan R, (...), Fischer A Translational Psychiatry 2025
Integrative analysis of miRNA expression profiles reveals distinct and common molecular mechanisms underlying broad diagnostic groups of severe mental disorders Solomon P, Kaurani L, (...), Poschmann J Molecular Psychiatry 2025
Alzheimer’s disease patient-derived high-molecular-weight tau impairs bursting in hippocampal neurons (Open Access) Harris SS, Ellingford R, (...), Busche MA Cell 2025
PP2A-B56α is a key determinant of cardiac protein phosphorylation and functional responses to β-adrenergic signalling (Open Access) Guran A, Ji Y, (...), Weeks KL Journal of Molecular and Cellular Cardiology Plus 2025
Brain-derived synaptic vesicles have an intrinsic ability to sequester tubulin (Open Access) Mimoso T, Korobeinikov A, (...), Reshetniak S bioRxiv 2025
Blood-derived microRNA signatures associated with hippocampal structure and atrophy rate: Findings from the Rhineland Study (Open Access) Melas K, Talevi V, (...), Breteler MM medRxiv 2025
Structure and function of otoferlin, a synaptic protein of sensory hair cells essential for hearing (Open Access) Chen H, Cretu C, (...), Moser T bioRxiv 2025
Chronic Vanadium Exposure Promotes Aggregation of Alpha‐Synuclein, Tau and Amyloid Beta in Mouse Brain (Open Access) Folarin OR, Olopade FE, (...), Outeiro TF Journal of Neurochemistry 2025
Endogenous SNAP-Tagging of Munc13-1 for Monitoring Synapse Nanoarchitecture (Open Access) Kowald M, Bachollet SPJT, (...), Lipstein N JACS Au 2025
SMIM20 promotes complex IV biogenesis and Ca2+ signaling in mice heart (Open Access) Boshnakovska A, Pronto JR, (...), Kremer LS Cell Reports 2025
Concept transfer of synaptic diversity from biological to artificial neural networks (Open Access) Hofmann M, Becker MFP, Tetzlaff C, Mäder P Nature Communications 2025
Role of Compensatory miRNA Networks in Cognitive Recovery from Heart Failure (Open Access) Gisa V, Islam MR, (...), Fischer A Non-Coding RNA 2025
Dual effect of α-synuclein disease variants on condensate formation (Open Access) Chandran A, Agarwal A, (...), Lautenschläger J bioRxiv 2025
NeuID, a novel neuron-specific lncRNA, resolves a key epigenetic mechanism linking gene silencing to Alzheimer’s disease (Open Access) Pradhan R, Petrovic Z, (...), Fischer A bioRxiv 2025
Circadian clock dysfunction in Parkinson’s disease: mechanisms, consequences, and therapeutic strategy (Open Access) Yalçin M, Grande V, Outeiro TF, Relόgio A npj Parkinsons Disease 2025
Phosphorylation of presynaptic PLPPR3 controls synaptic vesicle release (Open Access) Kroon C, Bareesel S, (...), Eickholt BJ iScience 2025
Condensates of synaptic vesicles and synapsin-1 mediate actin sequestering and polymerization (Open Access) Chhabra A, Hoffmann C, (...), Milovanović D EMBO Journal 2025
Altered translation elongation contributes to key hallmarks of aging in the killifish brain Di Fraia D, Marino A, (...), Ori A Science 2025
Long-term potentiation-induced changes in actin dynamics and spine geometry persist on the timescale of the synaptic tag (Open Access) Thomas M, Bogaciu C, Rizzoli SO, Fauth M Communications Biology 2025
Selective ubiquitination of drug-like small molecules by the ubiquitin ligase HUWE1 (Open Access) Orth B, Pohl P, (...), Lorenz S Nature Communications 2025
The Brownian dynamics simulator PyRID for reacting and interacting particles written in Python (Open Access) Becker M, Safari N, Tetzlaff C Cell Reports Methods 2025
Neddylation regulates the development and function of glutamatergic neurons (Open Access) Torres J, Vural Z, (...), Tirard M Communications Biology 2025
A Leishmania virulence factor harnesses an allosteric kinase switch to regulate its ubiquitin ligase activity (Open Access) Fokkens TJ, Rauh ET, (...), Lorenz S Molecular Cell 2025
Metabolite-enhanced normothermic machine perfusion improves kidney transplant viability (Open Access) Czogalla J, Hausmann F, (...), Puelles VG JCI Insight 2025
Structure and function of otoferlin, a synaptic protein of sensory hair cells essential for hearing (Open Access) Chen H, Cretu C, (...), Moser T Science Advances 2025
Representation learning in cerebellum-like structures (Open Access) Rudelt L, Mikulasch F, Priesemann V, Castro AF arXiv 2025
SynapseNet: Deep learning for automatic synapse reconstruction (Open Access) Muth S, Moschref F, (...), Pape C Molecular Biology of the Cell 2025
Charting the nanotopography of inner hair cell synapses using MINFLUX nanoscopy (Open Access) Kapoor R, Kim H, (...), Moser T Science Advances 2025
Brain-derived synaptic vesicles have an intrinsic ability to sequester tubulin (Open Access) Mimoso T, Korobeinikov A, (...), Reshetniak S BMC Biology 2025
lncRNA 3222401L13Rik/ENSG00000272070 modulates microglial inflammatory programs in association with PU.1 (Open Access) Pradhan R, Sakib MS, (...), Fischer A bioRxiv 2025
Nuclear Alpha‐Synuclein: Mechanisms and Implications for Synucleinopathies Outeiro TF, Koss DJ Movement Disorders 2025
Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function (Open Access) Asadollahi R, Ahmad A, (...), Lipstein N Nature Genetics 2025
A versatile microfluidics platform for enhanced multi-target super-resolution microscopy (Open Access) Basak S, Chi-Vu K, (...), Tsukanov R bioRxiv 2025
Ca2+-Triggered (de)ubiquitination Events in Synapses (Open Access) Ainatzi S, Kaufmann SV, (...), Urlaub H Molecular & Cellular Proteomics 2025
GARLH regulates neuroligin preference for excitatory versus inhibitory synapses Yamasaki T, Konno K, (...), Tomita S Journal of Cell Biology 2025
Uncovering the Complexity of Synucleinopathies: An Ongoing Tale Between Proteins and Lipids (Open Access) Flores‐León M, Outeiro TF Movement Disorders 2025
Self-blinking dye restores efficient use of nanobodies in single-molecule localization microscopy (Open Access) Basak S, Inamdar K, (...), Opazo F bioRxiv 2025
Channelrhodopsin variants for high-rate optogenetic neurostimulation at low light intensities (Open Access) Roos L, Garrido-Charles A, (...), Mager T EMBO Molecular Medicine 2025
Glycation of alpha-synuclein enhances aggregation and neuroinflammatory responses (Open Access) Vasili E, König A, (...), Outeiro TF npj Parkinson's Disease 2025
Super-resolution microscopy of mitochondrial mRNAs (Open Access) Stoldt S, Maass F, (...), Jakobs S Nature Communications 2025
Landscape of Target State Directed Processes in Living Systems (Open Access) Lenner N, Häring M, Eule S, Großhans J, Wolf F PRX Life 2025
In situ architecture of the human prohibitin complex (Open Access) Lange F, Ratz M, (...), Jakobs S Nature Cell Biology 2025
Autonomous bioluminescence emission from transgenic mice (Open Access) Kiszka KA, Dullin C, (...), Gregor C Science Advances 2025
Power-law adaptation in the presynaptic vesicle cycle (Open Access) Mikulasch FA, Georgiev SV, Rudelt L, Rizzoli SO, Priesemann V Communications Biology 2025
Poster: Integration of Open Source electronic laboratory notebooks for the biomedical Research Data Management Framework at Göttingen Campus (Open Access) Smolorz SA, Mathes T, (...), Kusch H Zenodo 2025
Synphilin-1 modulates alpha-synuclein assembly, release and uptake (Open Access) Lázaro DF, Amen T, (...), Outeiro TF npj Parkinsons Disease 2025
Lead as an environmental toxicant in models of synucleinopathies (Open Access) Shvachiy L, Amaro-Leal A, Machado F, Rocha I, Geraldes V, Outeiro TF Chemosphere 2025
A novel alpha-synuclein G14R missense variant is associated with atypical neuropathological features (Open Access) Brücke C, Al-Azzani M, (...), Outeiro TF Molecular Neurodegeneration 2025
Glutamatergic synaptic resilience to overexpressed human alpha-synuclein (Open Access) Santos PI, García-Plaza IH, (...), Outeiro TF npj Parkinsons Disease 2025
Paralemmin-1 controls the nanoarchitecture of the neuronal submembrane cytoskeleton (Open Access) Macarrón-Palacios V, Hubrich J, (...), Kilimann MW Science Advances 2025
Intersectin and endophilin condensates prime synaptic vesicles for release site replenishment (Open Access) Ogunmowo TH, Hoffmann C, (...), Watanabe S Nature Neuroscience 2025
Regulation of Zbp1 by miR-99b-5p in microglia controls the development of schizophrenia-like symptoms in mice (Open Access) Kaurani L, Islam MR, (...), Fischer A EMBO Journal 2024
Gender-Specific Effects on the Cardiorespiratory System and Neurotoxicity of Intermittent and Permanent Low-Level Lead Exposures (Open Access) Shvachiy L, Amaro-Leal A, Machado F, Rocha I, Outeiro TF, Geraldes V Biomedicines 2024
Author Correction: Mechanisms of simultaneous linear and nonlinear computations at the mammalian cone photoreceptor synapse (Open Access) Grabner CP, Futagi D, (...), DeVries SH Nature Communications 2024
Spatial proteomics in neurons at single-protein resolution (Open Access) Unterauer EM, Shetab Boushehri S, (...), Jungmann R Cell 2024
Membrane fission via transmembrane contact (Open Access) Spencer RKW, Santos-Pérez I, Rodríguez-Renovales I, Martinez Galvez JM, Shnyrova AV, Müller M Nature Communications 2024
Complexin has a dual synaptic function as checkpoint protein in vesicle priming and as a promoter of vesicle fusion (Open Access) López-Murcia FJ, Lin K, (...), Taschenberger H Proceedings of the National Academy of Sciences of the United States of America 2024
α-Synuclein triggers cofilin pathology and dendritic spine impairment via a PrPC-CCR5 dependent pathway (Open Access) Oliveira da Silva MI, Santejo M, (...), Liz MA Cell Death & Disease 2024
Three-dimensional multi-target super-resolution microscopy of cells using Metal-Induced Energy Transfer and DNA-PAINT (Open Access) Oleksiievets N, Mougios N, (...), Tsukanov R bioRxiv 2024
DISSECT: deep semi-supervised consistency regularization for accurate cell type fraction and gene expression estimation (Open Access) Khatri R, Machart P, Bonn S Genome Biology 2024
Different states of synaptic vesicle priming explain target cell type–dependent differences in neurotransmitter release (Open Access) Aldahabi M, Neher E, Nusser Z Proceedings of the National Academy of Sciences of the United States of America 2024
An aldehyde-crosslinking mitochondrial probe for STED imaging in fixed cells (Open Access) Chen J, Stephan T, (...), Chen Z Proceedings of the National Academy of Sciences of the United States of America 2024
Integrative Analysis of miRNA Expression Profiles Reveals Distinct and Common Molecular Mechanisms Underlying Broad Diagnostic Groups of Severe Mental Disorders (Open Access) Poschmann J, Solomon P, (...), Heilbronner U Researchsquare 2024
A role for astrocytic miR-129-5p in Frontotemporal Dementia (Open Access) Kaurani L, Pradhan R, (...), Fischer A bioRxiv 2024
Coordinating mitochondrial translation with assembly of the OXPHOS complexes (Open Access) Kremer LS, Rehling P Human Molecular Genetics 2024
Nanobodies against the myelin enzyme CNPase as tools for structural and functional studies (Open Access) Markusson S, Raasakka A, (...), Kursula P bioRxiv 2024
The lack of synapsin alters presynaptic plasticity at hippocampal mossy fibers in male mice (Open Access) Bruentgens F, Moreno Velasquez L, (...), Orlando M eNeuro 2024
Transient pores in hemifusion diaphragms (Open Access) Spencer R, Smirnova Y, Soleimani A, Müller M Biophysical Journal 2024
Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target (Open Access) Caldi Gomes L, Hänzelmann S, (...), Lingor P Nature Communications 2024
Interfering with aggregated α-synuclein in advanced melanoma leads to a major upregulation of MHC class II proteins (Open Access) Fokken C, Silbern I, (...), Becker D Melanoma Research 2024
Versatile nanobody-based approach to image, track and reconstitute functional Neurexin-1 in vivo (Open Access) Vicidomini R, Choudhury SD, (...), Serpe M Nature Communications 2024
Peripheral whole blood microRNA expression in relation to vascular function: a population-based study (Open Access) Talevi V, Melas K, (...), Breteler MM Journal of Translational Medicine 2024
PRDM16-DT: A Brain and Astrocyte-Specific lncRNA Implicated in Alzheimer’s Disease (Open Access) Schröder S, Fuchs U, (...), Fischer A bioRxiv 2024
The TOM complex from an evolutionary perspective and the functions of TOMM70 Özdemir M, Dennerlein S Biological Chemistry 2024
Author Correction: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons (Open Access) Riemenschneider H, Guo Q, (...), Edbauer D EMBO Reports 2024
Synthesis and Semi‐Synthesis of Alpha‐Synuclein: Insight into the Chemical Complexity of Synucleinopathies (Open Access) Gatzemeier LM, Meyer F, Outeiro TF Chembiochem 2024
Preparing primary sandwich hippocampal neuron cultures for cryo-electron tomography v1 (Open Access) Domart F, Petrovic A, Do TT, Siegert A, Dresbach T, Fernández-Busnadiego R protocols.io 2024
The DNA-PAINT palette: a comprehensive performance analysis of fluorescent dyes (Open Access) Steen PR, Unterauer EM, (...), Jungmann R Nature Methods 2024
STED super-resolution microscopy of mitochondrial translocases Schweighofer SV, Inamdar K, Jans DC, Jakobs S Methods in Enzymology 2024
A Technique to Perform Structure–Function Analysis of Synapses Wichmann C, Michanski S Neuromethods 2024
Blood‐derived microRNAs are related to cognitive domains in the general population (Open Access) Melas K, Talevi V, (...), Breteler MMB Alzheimers & Dementia 2024
Circulating microRNAs are related to cognitive domains in the general population (Open Access) Melas K, Talevi V, (...), Breteler MM medRxiv 2024
Calcium-triggered (de)ubiquitination events in synapses (Open Access) Ainatzi S, Kaufmann SV, (...), Urlaub H bioRxiv 2024
Power-law adaptation in the presynaptic vesicle cycle (Open Access) Mikulasch FA, Georgiev SV, Rudelt L, Rizzoli S, Priesemann V bioRxiv 2024
The plasma miRNAome in ADNI: Signatures to aid the detection of at‐risk individuals (Open Access) Krüger DM, Pena‐Centeno T, (...), Fischer A Alzheimers & Dementia 2024
Plasma miRNAs across the Alzheimer's disease continuum: Relationship to central biomarkers (Open Access) Liu S, Park T, (...), Nho K Alzheimers & Dementia 2024
Membrane trafficking of synaptic adhesion molecules (Open Access) Bogaciu CA, Rizzoli SO Journal of Physiology-London 2024
One-step nanoscale expansion microscopy reveals individual protein shapes (Open Access) Shaib AH, Chouaib AA, (...), Rizzoli SO Nature Biotechnology 2024
NanoPlex: a universal strategy for fluorescence microscopy multiplexing using nanobodies with erasable signals (Open Access) Mougios N, Cotroneo ER, (...), Opazo F Nature Communications 2024
Lead as a toxic environmental toxicant in models of synucleinopathies (Open Access) Shvachiy L, Amaro-Leal Â, Machado F, Rocha I, Geraldes V, Outeiro TF bioRxiv 2024
Endogenous tagging of Munc13-1 with a SNAP tag as a tool for monitoring synapse nanoarchitecture (Open Access) Kowald M, Bachollet SPJT, (...), Lipstein N bioRxiv 2024
The synaptic vesicle cluster as a controller of pre‐ and postsynaptic structure and function (Open Access) Reshetniak S, Bogaciu CA, (...), Rizzoli SO Journal of Physiology-London 2024
A novel alpha-synuclein G14R missense variant is associated with atypical neuropathological features (Open Access) Brücke C, Al-Azzani M, (...), Outeiro TF medRxiv 2024
Impact of Phosphorylation on the Physiological Form of Human alpha-Synuclein in Aqueous Solution (Open Access) de Bruyn E, Dorn AE, (...), Carloni P Journal of Chemical Information and Modeling 2024
Deletion of a core APC/C component reveals APC/C function in regulating neuronal USP1 levels and morphology (Open Access) Day JL, Tirard M, Brose N Frontiers in Molecular Neuroscience 2024
Synapses learn to utilize stochastic pre-synaptic release for the prediction of postsynaptic dynamics (Open Access) Kappel D, Tetzlaff C PLOS Computational Biology 2024
α-Synuclein plastic antibody applied to monitor monomeric structures and discriminate aggregated forms in human CSF (Open Access) da Silva IS, Cardoso AR, (...), Sales MGF Biosensors and Bioelectronics 2024
Morphology and inter-vesicle distances in condensates of synaptic vesicles and synapsin Neuhaus C, Alfken J, (...), Salditt T Biophysical Journal 2024
Plastic Arbor: a modern simulation framework for synaptic plasticity $\unicode{x2013}$ from single synapses to networks of morphological neurons (Open Access) Luboeinski J, Schmitt S, Kamalabad SS, Hater T, Bösch F, Tetzlaff C arXiv 2024
SynapseNet: Deep Learning for Automatic Synapse Reconstruction (Open Access) Muth S, Moschref F, (...), Pape C bioRxiv 2024
Nanobodies against the myelin enzyme <scp>CNPase</scp> as tools for structural and functional studies (Open Access) Markusson S, Raasakka A, (...), Kursula P Journal of Neurochemistry 2024
A microscopy-based screen identifies cellular kinases modulating mitochondrial translation (Open Access) Yousefi R, Cruz-Zaragoza LD, (...), Pacheu-Grau D Cell Reports 2024
The α-Synuclein Seed Amplification Assay: Interpreting a Test of Parkinson’s Pathology Espay AJ, Lees AJ, (...), Manfredsson FP Parkinsonism & Related Disorders 2024
New insights into the molecular architecture of neurons by cryo-electron tomography (Open Access) Petrovic A, Do TT, Fernández-Busnadiego R Current Opinion in Neurobiology 2024
Molecular Dynamics Trajectories Exploring the Impact of Phosphorylation on the Physiological Form of Human alpha-Synuclein in Aqueous Solution (Open Access) de Bruyn E, Dorn A, (...), Carloni P Zenodo 2024
Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver (Open Access) Aich A, Boshnakovska A, (...), Rehling P Nature Communications 2024
Paralemmin-1 controls the nanoarchitecture of the neuronal submembrane cytoskeleton (Open Access) Macarrón-Palacios V, Hubrich J, (...), Kilimann MW bioRxiv 2024
Morphological correlates of synaptic protein turnover in the mouse brain (Open Access) Li F, Bahr JN, (...), Rizzoli SO Life Science Alliance 2024
A minor impact of VGLUT1 expression level on quantal size revealed through the characterization of VGLUT1<sup>mEos2</sup>knock-down new mouse model (Open Access) Zhang XM, François U, (...), Herzog E bioRxiv 2024
Fission of double-membrane tubes under tension (Open Access) Spencer RK, Santos-Pérez I, Shnyrova AV, Müller M Biophysical Journal 2024
Neddylation regulates the development and function of excitatory neurons (Open Access) Torres J, Vural Z, (...), Tirard M bioRxiv 2024
Modeling Emergent Dynamics Arising from Synaptic Tagging and Capture at the Network Level Luboeinski J, Tetzlaff C Synaptic Tagging and Capture 2024
Differences in the consolidation by spontaneous and evoked ripples in the presence of active dendrites (Open Access) Jauch J, Becker M, Tetzlaff C, Fauth MJ PLOS Computational Biology 2024
PHluorin-conjugated secondary nanobodies as a tool for measuring synaptic vesicle exo- and endocytosis (Open Access) Georgiev SV, Rizzoli SO bioRxiv 2024
Lead as an Environmental Toxicant in Models of Synucleinopathies (Open Access) Geraldes V, Shvachiy L, Amaro-Leal A, Machado F, Rocha I, Outeiro TF Social Science Research Network 2024
The epitranscriptomic m6A RNA modification modulates synaptic function in ageing and in a mouse model of synucleinopathy (Open Access) Chopra A, Xylaki M, (...), Outeiro TF bioRxiv 2024
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Towards a biological diagnosis of PD (Open Access) Chopra A, Lang AE, Höglinger G, Outeiro TF Parkinsonism & Related Disorders 2024
Substitution of Met-38 to Ile in γ-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid (Open Access) Aubrey LD, Ninkina N, (...), Radford SE Proceedings of the National Academy of Sciences of the United States of America 2024
Advancing cell biology with nanoscale fluorescence imaging: essential practical considerations (Open Access) DʼEste E, Lukinavičius G, Lincoln R, Opazo F, Fornasiero EF Trends in Cell Biology 2024
H3 Acetylation-Induced Basal Progenitor Generation and Neocortex Expansion Depends on the Transcription Factor Pax6 (Open Access) Sokpor G, Kerimoglu C, (...), Tuoc T Biology-Basel 2024
Vesicle condensation induced by synapsin: condensate size, geometry, and vesicle shape deformations (Open Access) Alfken J, Neuhaus C, (...), Salditt T European Physical Journal E 2024
Dynamic gain decomposition reveals functional effects of dendrites, ion channels and input statistics in population coding Zhang C, Revah O, Wolf F, Neef A Journal of Neuroscience 2024
Subcellular protein turnover in human neural progenitor cells revealed by correlative electron microscopy and nanoscale secondary ion mass spectrometry imaging (Open Access) Lork AA, Rabasco S, Ernst C, du Toit A, Rizzoli SO, Phan NTN Chemical Science 2024
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Inhibition of 26S proteasome activity by α‐synuclein is mediated by the proteasomal chaperone Rpn14/PAAF1 (Open Access) Galka D, Ali TT, (...), Braus GH Aging Cell 2024
Synphilin-1 as a modulator of aSyn assembly (Open Access) Lázaro DF, Amen T, (...), Outeiro TF bioRxiv 2024
A Single-Cell Transcriptomic Analysis of the Mouse Hippocampus After Voluntary Exercise (Open Access) Methi A, Islam MR, (...), Fischer A Molecular Neurobiology 2024
Comprehensive transcriptome analysis reveals altered mRNA splicing and post-transcriptional changes in the aged mouse brain (Open Access) Kumar NH, Kluever V, (...), Fornasiero EF Nucleic Acids Research 2024
NanoPlex: a universal strategy for fluorescence microscopy multiplexing using nanobodies with erasable signals (Open Access) Mougios N, Cotroneo ER, (...), Opazo F bioRxiv 2024
Formation of memory assemblies through the DNA-sensing TLR9 pathway (Open Access) Jovasevic V, Wood EM, (...), Radulovic J Nature 2024
Mechanisms of simultaneous linear and nonlinear computations at the mammalian cone photoreceptor synapse (Open Access) Grabner CP, Futagi D, (...), DeVries SH Nature Communications 2023
Changes in α-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson’s Disease (Open Access) Brembati V, Faustini G, Longhena F, Outeiro TF, Bellucci A International Journal of Molecular Sciences 2023
Tunable synaptic working memory with volatile memristive devices (Open Access) Ricci S, Kappel D, Tetzlaff C, Ielmini D, Covi E Neuromorphic Computing and Engineering 2023
Protein nanobarcodes enable single-step multiplexed fluorescence imaging (Open Access) de Jong-Bolm D, Sadeghi M, (...), Rizzoli SO PLOS Biology 2023
Ketamine potentiates a central glutamatergic presynapse (Open Access) Eshra A, Lipstein N, Hallermann S bioRxiv 2023
An intellectual-disability-associated mutation of the transcriptional regulator NACC1 impairs glutamatergic neurotransmission (Open Access) Daniel JA, Elizarova S, (...), Tirard M Frontiers in Molecular Neuroscience 2023
Intersectin and Endophilin condensates prime synaptic vesicles for release site replenishment (Open Access) Ogunmowo T, Hoffmann C, (...), Watanabe S bioRxiv 2023
Neuronal activity modulates the incorporation of newly translated PSD-95 into a robust structure as revealed by STED and MINFLUX (Open Access) Gürth C, do Rego Barros Fernandes Lima MA, (...), D’Este E bioRxiv 2023
DISCERN: deep single-cell expression reconstruction for improved cell clustering and cell subtype and state detection (Open Access) Hausmann F, Ergen C, (...), Bonn S Genome Biology 2023
Neurofilament Levels in Dendritic Spines Associate with Synaptic Status (Open Access) Gürth C, do Rego Barros Fernandes Lima MA, Macarrón Palacios V, Cereceda Delgado AR, Hubrich J, D’Este E Cells 2023
Spatial proteomics in neurons at single-protein resolution (Open Access) Unterauer EM, Boushehri SS, (...), Jungmann R bioRxiv 2023
An Analytically Solvable Model of Firing Rate Heterogeneity in Balanced State Networks (Open Access) Schmidt A, Hiemeyer P, Wolf F arXiv 2023
Lyapunov spectra of chaotic recurrent neural networks (Open Access) Engelken R, Wolf F, Abbott LF Physical Review Research 2023
miR-101a-3p Impairs Synaptic Plasticity and Contributes to Synucleinopathy (Open Access) Xylaki M, Paiva I, (...), Outeiro TF Journal of Parkinson’s Disease 2023
Uncovering the molecular link between lead toxicity and Parkinson’s disease Shvachiy L, Geraldes V, Outeiro T Antioxidants & Redox Signaling 2023
Trafficking proteins show limited differences in mobility across different postsynaptic spines (Open Access) Mougios N, Opazo F, Rizzoli SO, Reshetniak S iScience 2023
Phase Separation in Biology and Disease; Current Perspectives and Open Questions (Open Access) Boeynaems S, Chong S, (...), Kriwacki R Journal of Molecular Biology 2023
Neurodegenerative disease of the brain: a survey of interdisciplinary approaches (Open Access) Davenport F, Gallacher J, (...), Zetterberg H Journal of The Royal Society Interface 2023
Deep learning enables fast, gentle STED microscopy (Open Access) Ebrahimi V, Stephan T, (...), Han KY bioRxiv 2023
Condensate biology of synaptic vesicle clusters (Open Access) Sansevrino R, Hoffmann C, Milovanovic D Trends in Neurosciences 2023
A versatile Synaptotagmin-1 nanobody provides perturbation-free live synaptic imaging and low linkage-error in super-resolution microscopy (Open Access) Villa Real KQZ, Mougios N, (...), Opazo F bioRxiv 2023
Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF (Open Access) Antoniou A, Auderset L, (...), Schneider A Cell Reports 2023
Alpha-synuclein oligomers activate nuclear factor of activated T-cells (NFAT) modulating apoptosis and synaptic homeostasis (Open Access) Sant'Anna R, Robbs BK, (...), Foguel D bioRxiv 2023
Conserved reduction of m6A RNA modifications during aging and neurodegeneration is linked to changes in synaptic transcripts (Open Access) Castro-Hernández R, Berulava T, (...), Fischer A Proceedings of the National Academy of Sciences of the United States of America 2023
The multifaceted mitochondrial OXA insertase (Open Access) Homberg B, Rehling P, Cruz-Zaragoza LD Trends in Cell Biology 2023
Intermittent Lead Exposure Induces Behavioral and Cardiovascular Alterations Associated with Neuroinflammation (Open Access) Shvachiy L, Amaro-Leal A, Outeiro TF, Rocha I, Geraldes V Cells 2023
Characterizing the differential distribution and targets of Sumo1 and Sumo2 in the mouse brain (Open Access) Suk TR, Nguyen TT, (...), Rousseaux MW iScience 2023
Impact of Phosphorylation on alpha-Synuclein Structural Determinants (Open Access) Dorn AE, de Bruyn E, (...), Carloni P bioRxiv 2023
Reverse-time analysis uncovers universality classes in directional biological dynamics (Open Access) Lenner N, Eule S, Großhans J, Wolf F arXiv 2023
Towards a Biological Definition of Parkinson’s Disease (Open Access) Höglinger GU, Adler CH, (...), Lang AE Preprints 2023
Expansion-enhanced super-resolution radial fluctuations enable nanoscale molecular profiling of pathology specimens (Open Access) Kylies D, Zimmermann M, (...), Puelles VG Nature Nanotechnology 2023
Reverse-time analysis and boundary classification of directional biological dynamics with multiplicative noise (Open Access) Lenner N, Häring M, Eule S, Großhans J, Wolf F arXiv 2023
Chemical Synthesis of Alpha‐Synuclein Proteins via Solid‐Phase Peptide Synthesis and Native Chemical Ligation (Open Access) Gatzemeier LM, Meyer F, Diederichsen U, Outeiro TF Chemistry-A European Journal 2023
A novel miR-99b-5p-Zbp1 pathway in microglia contributes to the pathogenesis of schizophrenia (Open Access) Kaurani L, Islam MR, (...), Fischer A bioRxiv 2023
Deep learning enables fast, gentle STED microscopy (Open Access) Ebrahimi V, Stephan T, (...), Han KY Communications Biology 2023
Is it all the RAGE? Defining the role of the receptor for advanced glycation end products in Parkinson's disease (Open Access) Gasparotto J, Somensi N, (...), Gelain DP Journal of Neurochemistry 2023
Tunable Synaptic Working Memory with Volatile Memristive Devices (Open Access) Ricci S, Kappel D, Tetzlaff C, Ielmini D, Covi E arXiv 2023
AI and protein structure and function in neurological disease: relevance to disease management Outeiro TF, Vieira TCRG Nature Reviews Neurology 2023
A Versatile Synaptotagmin‐1 Nanobody Provides Perturbation‐Free Live Synaptic Imaging And Low Linkage‐Error in Super‐Resolution Microscopy (Open Access) Queiroz Zetune Villa Real K, Mougios N, (...), Opazo F Small Methods 2023
Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto‐axonal target in late‐stage Parkinson's disease (Open Access) Warth Perez Arias CC, Silbern I, (...), Lingor P Journal of Neurochemistry 2023
Metabolic switch from fatty acid oxidation to glycolysis in knock-in mouse model of Barth syndrome (Open Access) Chowdhury A, Boshnakovska A, (...), Rehling P EMBO Molecular Medicine 2023
Aggregation and beyond: alpha-synuclein-based biomarkers in synucleinopathies Chopra A, Outeiro TF Brain 2023
The alpha-synuclein oligomers activate nuclear factor of activated T-cell (NFAT) modulating synaptic homeostasis and apoptosis (Open Access) Sant’Anna R, Robbs BK, (...), Foguel D Molecular Medicine 2023
A viral ADP-ribosyltransferase attaches RNA chains to host proteins (Open Access) Wolfram-Schauerte M, Pozhydaieva N, (...), Höfer K Nature 2023
Boosting of neural circuit chaos at the onset of collective oscillations (Open Access) Palmigiano A, Engelken R, Wolf F eLife 2023
Increased alpha-synuclein and neuroinflammation in the substantia nigra triggered by systemic inflammation are reversed by targeted inhibition of the receptor for advanced glycation end products (RAGE) Oppermann Peixoto D, Bittencourt RR, (...), Pens Gelain D Journal of Neurochemistry 2023
Baseline levels of miR-223-3p correlate with the effectiveness of electroconvulsive therapy in patients with major depression (Open Access) Kaurani L, Besse M, (...), Zilles-Wegner D Translational Psychiatry 2023
Fibroblast growth factor 9 (FGF9) mediated neurodegeneration: implications for progressive multiple sclerosis? (Open Access) Thümmler K, Wrzos C, (...), Linington C Neuropathology and Applied Neurobiology 2023
Phosphatases modified by LH signaling in ovarian follicles: testing their role in regulating the NPR2 guanylyl cyclase Egbert JR, Silbern I, (...), Jaffe LA Biology of Reproduction 2023
Control of intracellular pH and bicarbonate by CO2 diffusion into human sperm (Open Access) Grahn E, Kaufmann SV, (...), Kaupp U Nature Communications 2023
Synapsin condensation controls synaptic vesicle sequestering and dynamics (Open Access) Hoffmann C, Rentsch J, (...), Milovanovic D Nature Communications 2023
PrP meets alpha‐synuclein: Molecular mechanisms and implications for disease (Open Access) Vieira TCRG, Barros CA, Domingues R, Outeiro TF Journal of Neurochemistry 2023
High-resolution analysis of bound Ca<sup>2+</sup>in neurons and synapses (Open Access) Bonnin EA, Golmohammadi A, Rehm R, Tetzlaff C, Rizzoli SO Life Science Alliance 2023
Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices (Open Access) Jentoft IM, Bäuerlein FJ, (...), Schuh M Cell 2023
ATG9 resides on a unique population of small vesicles in presynaptic nerve terminals Binotti B, Ninov M, (...), Jahn R Autophagy 2023
FAT10 is phosphorylated by IKKβ to inhibit the antiviral type-I interferon response (Open Access) Saxena K, Roverato ND, (...), Aichem A Life Science Alliance 2023
Prediction mismatch responses arise as corrections of a predictive spiking code (Open Access) van Driel K, Rudelt L, Priesemann V, Mikulasch FA bioRxiv 2023
Excess Phosphoserine-129 α-Synuclein Induces Synaptic Vesicle Trafficking and Declustering Defects at a Vertebrate Synapse (Open Access) Wallace JN, Crockford ZC, (...), Morgan JR Molecular Biology of the Cell 2023
Developmental changes of the mitochondria in the murine anteroventral cochlear nucleus (Open Access) Hintze A, Lange F, (...), Wichmann C iScience 2023
Lipid vesicle pools studied by passive X-ray microrheology (Open Access) Czajka T, Neuhaus C, (...), Salditt T European Physical Journal E 2023
Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory versus Inhibitory Synapses (Open Access) Altas B, Tuffy LP, (...), Poulopoulos A Biological Psychiatry 2023
B36.00008: Membrane fusion as a pathway to fission (Open Access) Spencer RK, Müller M APS March Meeting 2024 2023
Age-dependent structural reorganization of utricular ribbon synapses (Open Access) Michanski S, Henneck T, (...), Wichmann C Frontiers in Cell and Developmental Biology 2023
Polychaetoid/ZO-1 strengthens cell junctions under tension while localizing differently than core adherens junction proteins (Open Access) Peifer M, Schmidt A, (...), Wolf F Molecular Biology of the Cell 2023
Boosting of neural circuit chaos at the onset of collective oscillations (Open Access) Palmigiano A, Engelken R, Wolf F eLife 2023
The long-loop recycling (LLR) of synaptic components as a question of economics (Open Access) Georgiev SV, Rizzoli SO Molecular and Cellular Neuroscience 2023
SparseProp: Efficient Event-Based Simulation and Training of Sparse Recurrent Spiking Neural Networks (Open Access) Engelken R arXiv 2023
Gel‐like inclusions of C‐terminal fragments of TDP‐43 sequester stalled proteasomes in neurons (Open Access) Riemenschneider H, Guo Q, (...), Edbauer D EMBO reports 2022
Visualizing proteins by expansion microscopy (Open Access) Shaib AH, Chouaib AA, (...), Rizzoli SO bioRxiv 2022
α-Synuclein Impacts on Intrinsic Neuronal Network Activity Through Reduced Levels of Cyclic AMP and Diminished Numbers of Active Presynaptic Terminals (Open Access) Leite K, Garg P, (...), Kügler S Frontiers in Molecular Neuroscience 2022
White matter integrity in mice requires continuous myelin synthesis at the inner tongue (Open Access) Meschkat M, Steyer AM, (...), Möbius W Nature Communications 2022
Visuomotor Mismatch Responses as a Hallmark of Explaining Away in Causal Inference Mikulasch FA, Rudelt L, Priesemann V Neural Computation 2022
Stress - Regulation of SUMO conjugation and of other Ubiquitin‐Like Modifiers Ilic D, Magnussen HM, Tirard M Seminars in Cell & Developmental Biology 2022
Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA (Open Access) Keil P, Wulf A, (...), Sträßer K Nucleic Acids Research 2022
Phorbolester-activated Munc13-1 and ubMunc13-2 exert opposing effects on dense-core vesicle secretion (Open Access) Houy S, Martins JS, Lipstein N, Sørensen JB eLife 2022
Neuromodulator-dependent synaptic tagging and capture retroactively controls neural coding in spiking neural networks (Open Access) Lehr AB, Luboeinski J, Tetzlaff C Scientific Reports 2022
Environmental enrichment enhances patterning and remodeling of synaptic nanoarchitecture as revealed by STED nanoscopy (Open Access) Wegner W, Steffens H, Gregor C, Wolf F, Willig KI eLife 2022
Ultrafast population coding and axo-somatic compartmentalization (Open Access) Zhang C, Hofmann D, Neef A, Wolf F PLOS Computational Biology 2022
Prion-like α-synuclein pathology in the brain of infants with Krabbe disease (Open Access) Hatton C, Ghanem SS, (...), Erskine D Brain 2022
Signals from the interface: protein nanoclusters stabilize biomolecular condensates (Open Access) Hoffmann C, Rankovic B, Milovanovic D Signal Transduct Target Ther 2022
Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation (Open Access) Torres-Garcia L, P. Domingues JM, (...), Li J Scientific Reports 2022
Identification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes (Open Access) Chang HF, Schirra C, (...), Rettig J Nature Communications 2022
Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3 Upmanyu N, Jin J, (...), Sambandan S Neuron 2022
Methods for multiscale structural and functional analysis of the mammalian cochlea Vogl C, Neef J, Wichmann C Molecular and Cellular Neuroscience 2022
DiSCERN - Deep Single Cell Expression ReconstructioN for improved cell clustering and cell subtype and state detection (Open Access) Hausmann F, Ergen-Behr C, (...), Bonn S bioRxiv 2022
Extracellular alpha-synuclein: Sensors, receptors, and responses (Open Access) Domingues R, Sant’Anna R, da Fonseca ACC, Robbs BK, Foguel D, Outeiro TF Neurobiology of Disease 2022
The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains (Open Access) Peña-Díaz S, Pujols J, (...), Ventura S Journal of Biological Chemistry 2022
Extracellular Matrix Recycling as a Novel Plasticity Mechanism With a Potential Role in Disease (Open Access) Dankovich TM, Rizzoli SO Frontiers in Cellular Neuroscience 2022
The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible (Open Access) Cassotta M ALTEX-Alternatives to Animal Experimentation 2022
Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses (Open Access) Chakrabarti R, Jaime Tobón LM, (...), Wichmann C bioRxiv 2022
Optimal precision and accuracy in 4Pi-STORM using dynamic spline PSF models (Open Access) Bates M, Keller-Findeisen J, (...), Hell SW Nature Methods 2022
An iodine-containing probe as a tool for molecular detection in secondary ion mass spectrometry (Open Access) Kabatas Glowacki S, Agüi-Gonzalez P, (...), Rizzoli SO Chemical Communications 2022
Aromaticity at position 39 in α‐synuclein: A modulator of amyloid fibril assembly and membrane‐bound conformations (Open Access) Buratti FA, Boeffinger N, (...), Fernández CO Protein Science 2022
Resolving the molecular architecture of the photoreceptor active zone with 3D-MINFLUX (Open Access) Grabner CP, Jansen I, (...), Moser T Science Advances 2022
JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species (Open Access) Santos CC, Cardim-Pires TR, (...), Silva VDA Neurotoxicity Research 2022
Ectosomes and exosomes modulate neuronal spontaneous activity Brás IC, Khani MH, (...), Outeiro TF Journal of Proteomics 2022
Glycation modulates glutamatergic signaling and exacerbates Parkinson’s disease-like phenotypes (Open Access) Chegão A, Guarda M, (...), Vicente Miranda H npj Parkinson's Disease 2022
Extracellular vesicles derived from the choroid plexus trigger the differentiation of neural stem cells (Open Access) Ditte Z, Silbern I, Ditte P, Urlaub H, Eichele G Journal of Extracellular Vesicles 2022
Focused ion beam‐scanning electron microscopy links pathological myelin outfoldings to axonal changes in mice lacking Plp1 or Mag (Open Access) Steyer AM, Buscham TJ, (...), Werner HB Glia 2022
Where is the error? Hierarchical predictive coding through dendritic error computation (Open Access) Mikulasch FA, Rudelt L, Wibral M, Priesemann V Trends in Neurosciences 2022
ERR2 and ERR3 promote the development of gamma motor neuron functional properties required for proprioceptive movement control (Open Access) Khan MN, Cherukuri P, (...), Marquardt T PLOS Biology 2022
Abstract: A10.00009 : The role of protein constriction in the fission of membrane tubes (Open Access) Spencer RK, Müller M APS March Meeting 2023 2022
Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies (Open Access) Koss DJ, Erskine D, (...), Outeiro TF Acta Neuropathologica Communications 2022
Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses (Open Access) Chakrabarti R, Jaime Tobón LM, (...), Wichmann C eLife 2022
Endogenous Levels of Alpha-Synuclein Modulate Seeding and Aggregation in Cultured Cells (Open Access) Vasili E, Dominguez-Meijide A, (...), Outeiro TF Molecular Neurobiology 2022
Alpha-synuclein overexpression induces epigenomic dysregulation of glutamate signaling and locomotor pathways (Open Access) Schaffner SL, Wassouf Z, (...), Kobor MS Human Molecular Genetics 2022
Age-dependent structural reorganization of utricular ribbon synapses (Open Access) Michanski S, Henneck T, (...), Wichmann C bioRxiv 2022
Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity Brás IC, Khani MH, (...), Outeiro TF Journal of Parkinsons Disease 2022
Conserved reduction of m<sup>6</sup>A marks during aging and neurodegeneration is linked to altered translation of synaptic transcripts (Open Access) Castro-Hernández R, Berulava T, (...), Fischer A bioRxiv 2022
Boosting of neural circuit chaos at the onset of collective oscillations (Open Access) Palmigiano A, Engelken R, Wolf F bioRxiv 2022
From Molecular to Functional Effects of Different Environmental Lead Exposure Paradigms (Open Access) Shvachiy L, Amaro-Leal A, Outeiro TF, Rocha I, Geraldes V Biology (Basel) 2022
The Synaptic Extracellular Matrix: Long-Lived, Stable, and Still Remarkably Dynamic (Open Access) Dankovich TM, Rizzoli SO Frontiers in Synaptic Neuroscience 2022
Alpha-Synuclein Antibody Characterization: Why Semantics Matters (Open Access) Outeiro TF Molecular Neurobiology 2021
Non-negative Matrix Factorization as a Tool to Distinguish Between Synaptic Vesicles in Different Functional States Neher E, Taschenberger H Neuroscience 2021
Exploring early time points of vimentin assembly in flow by fluorescence fluctuation spectroscopy Perego E, Köster S Lab on a Chip 2021
NanoSIMS observations of mouse retinal cells reveal strict metabolic controls on nitrogen turnover (Open Access) Bonnin EA, Fornasiero EF, Lange F, Turck CW, Rizzoli SO BMC Molecular and Cell Biology 2021
Photoactivatable Fluorescent Dyes with Hydrophilic Caging Groups and Their Use in Multicolor Nanoscopy (Open Access) Butkevich AN, Weber M, Cereceda Delgado AR, Ostersehlt LM, D’Este E, Hell SW Journal of the American Chemical Society 2021
Evaluation and Optimization of High-Field Asymmetric Waveform Ion-Mobility Spectrometry for Multiplexed Quantitative Site-Specific N-Glycoproteomics (Open Access) Fang P, Ji Y, (...), Urlaub H Analytical Chemistry 2021
Stable but not rigid: Chronic in vivo STED nanoscopy reveals extensive remodeling of spines, indicating multiple drivers of plasticity (Open Access) Steffens H, Mott AC, (...), Willig KI Science Advances 2021
Correlative fluorescence microscopy, transmission electron microscopy and secondary ion mass spectrometry (CLEM-SIMS) for cellular imaging (Open Access) Lange F, Agüi-Gonzalez P, Riedel D, Phan NTN, Jakobs S, Rizzoli SO PLoS One 2021
Challenges facing quantitative large-scale optical super-resolution, and some simple solutions (Open Access) Dankovich TM, Rizzoli SO iScience 2021
Relative Quantification of Phosphorylated and Glycosylated Peptides from the Same Sample Using Isobaric Chemical Labelling with a Two-Step Enrichment Strategy Silbern I, Fang P, Ji Y, Christof L, Urlaub H, Pan K Methods in Molecular Biology 2021
Intranuclear immunostaining-based FACS protocol from embryonic cortical tissue (Open Access) Sakib MS, Sokpor G, Nguyen HP, Fischer A, Tuoc T STAR Protocols 2021
Exploring new roles for actin upon LTP induction in dendritic spines (Open Access) Bonilla-Quintana M, Wörgötter F Scientific Reports 2021
Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders (Open Access) Erskine D, Koss D, Korolchuk VI, Outeiro TF, Attems J, McKeith I Acta Neuropathologica 2021
Memory consolidation and improvement by synaptic tagging and capture in recurrent neural networks (Open Access) Luboeinski J, Tetzlaff C Communications Biology 2021
Correction to: The Coding and Small Non-coding Hippocampal Synaptic RNAome (Open Access) Epple R, Krüger D, (...), Fischer A Molecular Neurobiology 2021
Sulthiame impairs mitochondrial function in vitro and may trigger onset of visual loss in Leber hereditary optic neuropathy (Open Access) Reinert M, Pacheu-Grau D, (...), Brockmann K Orphanet Journal of Rare Diseases 2021
Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation (Open Access) Jafari M, Schumacher A, (...), Kerschensteiner M Nature Neuroscience 2021
Hippocampal neurons respond to brain activity with functional hypoxia (Open Access) Butt UJ, Steixner-Kumar AA, (...), Ehrenreich H Molecular Psychiatry 2021
Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo (Open Access) Dominguez-Meijide A, Parrales V, (...), Outeiro TF Neurobiology of Disease 2021
Protein phosphorylation in depolarized synaptosomes: Dissecting primary effects of calcium from synaptic vesicle cycling (Open Access) Silbern I, Pan K, (...), Jahn R Molecular & Cellular Proteomics 2021
Monitoring mitochondrial translation in living cells (Open Access) Yousefi R, Fornasiero EF, (...), Pacheu‐Grau D EMBO Reports 2021
Reproducing asymmetrical spine shape fluctuations in a model of actin dynamics predicts self-organized criticality (Open Access) Bonilla-Quintana M, Wörgötter F, D’Este E, Tetzlaff C, Fauth M Scientific Reports 2021
Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients (Open Access) Zhao Y, Kilian C, (...), Krebs CF Science Immunology 2021
The Coding and Small Non-coding Hippocampal Synaptic RNAome (Open Access) Epple R, Krüger D, (...), Fischer A Molecular Neurobiology 2021
Cofilin pathology is a new player on α-synuclein-induced spine impairment in models of hippocampal synucleinopathy (Open Access) Oliveira da Silva MI, Santejo M, (...), Liz M bioRxiv 2021
Ultrastructural maturation of endbulb of Held active zones comparing wild-type and otoferlin-deficient mice (Open Access) Hintze A, Gültas M, Semmelhack EA, Wichmann C iScience 2021
The vesicle cluster as a major organizer of synaptic composition in the short-term and long-term (Open Access) Reshetniak S, Rizzoli SO Current Opinion in Cell Biology 2021
RIM-Binding Proteins Are Required for Normal Sound-Encoding at Afferent Inner Hair Cell Synapses (Open Access) Krinner S, Predoehl F, Burfeind D, Vogl C, Moser T Frontiers in Molecular Neuroscience 2021
The effect of polydispersity, shape fluctuations and curvature on small unilamellar vesicle small-angle X-ray scattering curves (Open Access) Chappa V, Smirnova Y, Komorowski K, Müller M, Salditt T Journal of Applied Crystallography 2021
Synapsin Condensates Recruit alpha-Synuclein (Open Access) Hoffmann C, Sansevrino R, (...), Milovanovic D Journal of Molecular Biology 2021
Presynaptic activity and protein turnover are correlated at the single-synapse level (Open Access) Jähne S, Mikulasch F, (...), Priesemann V Cell Reports 2021
Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex (Open Access) Ulmke PA, Sakib MS, (...), Tuoc T Stem Cell Reports 2021
Secondary Ion Mass Spectrometry Imaging Reveals Changes in the Lipid Structure of the Plasma Membranes of Hippocampal Neurons following Drugs Affecting Neuronal Activity (Open Access) Agüi-Gonzalez P, Guobin B, Gomes de Castro MA, Rizzoli SO, Phan NTN ACS Chemical Neuroscience 2021
Gold-conjugated Nanobodies for Targeted Imaging using High-resolution Secondary Ion Mass Spectrometry (Open Access) Agüi-Gonzalez P, Dankovich TM, Opazo F, Rizzoli SO, Phan NT Preprints 2021
Alpha-synuclein induces epigenomic dysregulation of glutamate signaling and locomotor pathways (Open Access) Schaffner SL, Wassouf Z, (...), Kobor MS bioRxiv 2021
Super-resolution microscopy informs on the molecular architecture of alpha-synuclein inclusions in model systems and in the human brain (Open Access) Weish P, Lazaro DF, (...), Outeiro TF bioRxiv 2021
RIM-Binding Protein 2 organizes Ca2+ channel topography and regulates release probability and vesicle replenishment at a fast central synapse (Open Access) Butola T, Alvanos T, (...), Moser T bioRxiv 2021
Dysfunction of RAB39B‐Mediated Vesicular Trafficking in Lewy Body Diseases (Open Access) Koss DJ, Campesan S, Giorgini F, Outeiro TF Movement Disorders 2021
A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines (Open Access) Helm MS, Dankovich TM, (...), Rizzoli SO Nature Neuroscience 2021
Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein (Open Access) Martinez Hernandez A, Silbern I, (...), Eichele G Frontiers in Neuroscience 2021
Allosteric transcription stimulation by RNA polymerase II super elongation complex Chen Y, Vos SM, Dienemann C, Ninov M, Urlaub H, Cramer P Molecular Cell 2021
Common molecular mechanisms underlie the transfer of alpha-synuclein, Tau and huntingtin and modulate spontaneous activity in neuronal cells (Open Access) Brás IC, Khani MH, (...), Outeiro TF bioRxiv 2021
Surface tension and viscosity of protein condensates quantified by micropipette aspiration (Open Access) Wang H, Kelley FM, Milovanovic D, Schuster BS, Shi Z Biophysical Reports 2021
Cellular Prion Protein Mediates α‐Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo (Open Access) Thom T, Schmitz M, (...), Zerr I Movement Disorders 2021
Differences in synaptic vesicle pool behavior between male and female hippocampal cultured neurons (Open Access) Sertel SM, Blumenstein W, Mandad S, Shomroni O, Salinas G, Rizzoli SO Scientific Reports 2021
Tubular microdomains of Rab7-endosomes retrieve TrkA, a mechanism disrupted in Charcot-Marie-Tooth 2B Markworth R, Dambeck V, (...), Burk K Journal of Cell Science 2021
Management of Metadata Types in Basic Cardiological Research (Open Access) Kusch H, Kossen R, (...), Nussbeck SY Studies in Health Technology and Informatics 2021
Bias-invariant RNA-sequencing metadata annotation (Open Access) Wartmann H, Heins S, Kloiber K, Bonn S Gigascience 2021
Principles of brain aging: Status and challenges of modeling human molecular changes in mice (Open Access) Kluever V, Fornasiero EF Ageing Research Reviews 2021
GMDS2021 ePoster and video teaser for DOI 10.3205/21gmds072 (Open Access) Kusch H, Bauer CR, (...), Sax U Göttingen Research Online / Data 2021
Exercise as a model to identify microRNAs linked to human cognition: a role for microRNA-409 and microRNA-501 (Open Access) Goldberg M, Islam MR, (...), Fischer A Translational Psychiatry 2021
The mammalian rod synaptic ribbon is essential for Cav channel facilitation and ultrafast synaptic vesicle fusion (Open Access) Grabner CP, Moser T eLife 2021
Munc13-1 is a Ca2+-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission (Open Access) Lipstein N, Chang S, (...), Brose N Neuron 2021
Heterogeneity of glutamatergic synapses: cellular mechanisms and network consequences (Open Access) Wichmann C, Kuner T Physiological Reviews 2021
Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy (Open Access) Kettwig M, Ternka K, (...), Gärtner J Nature Communications 2021
Three-dimensional virtual histology of the cerebral cortex based on phase-contrast X-ray tomography (Open Access) Eckermann M, van der Meer F, (...), Salditt T Biomedical Optics Express 2021
Punctuated evolution of visual cortical circuits? Evidence from the large rodent Dasyprocta leporina, and the tiny primate Microcebus murinus (Open Access) Schmidt KE, Wolf F Current Opinion in Neurobiology 2021
Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron‐enriched genes (Open Access) Michurina A, Sakib MS, (...), Fischer A EMBO Journal 2021
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R (Open Access) Dankovich TM, Kaushik R, (...), Rizzoli SO Nature Communications 2021
Endogenous Levels of Alpha-synuclein Modulate Seeding and Aggregation in Cultured Cells (Open Access) Vasili E, Dominguez-Meijide A, (...), Outeiro T Researchsquare 2021
RIM-Binding Protein 2 Organizes Ca2+ Channel Topography and Regulates Release Probability and Vesicle Replenishment at a Fast Central Synapse (Open Access) Butola T, Alvanos T, (...), Moser T The Journal of Neuroscience 2021
A microRNA signature that correlates with cognition and is a target against cognitive decline (Open Access) Islam MR, Kaurani L, (...), Fischer A EMBO Molecular Medicine 2021
Conditional Loss of BAF (mSWI/SNF) Scaffolding Subunits Affects Specification and Proliferation of Oligodendrocyte Precursors in Developing Mouse Forebrain (Open Access) Abbas E, Hassan MA, (...), Tuoc T Frontiers in Cell and Developmental Biology 2021
Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease (Open Access) Oliveira LMA, Gasser T, (...), Outeiro TF npj Parkinson's Disease 2021
Co-localization of different neurotransmitter transporters on synaptic vesicles is sparse except of VGLUT1 and ZnT3 (Open Access) Upmanyu N, Jin J, (...), Sambandan S bioRxiv 2021
Monitoring Alpha-Synuclein – Tau Interactions In Vitro and In Vivo Using Bimolecular Fluorescence Complementation (Open Access) Torres-Garcia L, Domingues JM, (...), Li J Researchsquare 2021
Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies (Open Access) Koss DJ, Erskine D, (...), Outeiro TF bioRxiv 2021
Resolving the molecular architecture of the photoreceptor active zone by MINFLUX nanoscopy (Open Access) Grabner CP, Jansen I, (...), Moser T bioRxiv 2021
Gold-Conjugated Nanobodies for Targeted Imaging Using High-Resolution Secondary Ion Mass Spectrometry (Open Access) Agüi-Gonzalez P, Dankovich TM, Rizzoli SO, Phan NTN Nanomaterials 2021
Kinetic coupling of the respiratory chain with ATP synthase, but not proton gradients, drives ATP production in cristae membranes Toth A, Meyrat A, (...), Ott M Proceedings of the National Academy of Sciences of the United States of America 2020
MINFLUX nanoscopy delivers 3D multicolor nanometer resolution in cells Gwosch KC, Pape JK, (...), Hell SW Nature Methods 2020
Leaflet-dependent distribution of PtdIns[4,5]P2 in supported model membranes Schäfer J, Nehls J, Schön M, Mey IP, Steinem C Langmuir 2020
Synucleinopathies: Where we are and where we need to go (Open Access) Brás IC, Dominguez‐Meijide A, (...), Outeiro TF Journal of Neurochemistry 2020
Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors Luo L, Ambrozkiewicz MC, (...), Craig AM Neuron 2020
Light Microscopy of Mitochondria at the Nanoscale Jakobs S, Stephan T, Ilgen P, Brüser C Annual Review of Biophysics 2020
Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses (Open Access) Maus L, Lee C, (...), Cooper BH Cell Reports 2020
Protein trapping leads to altered synaptic proteostasis in synucleinopathies (Open Access) Santos PI, Outeiro TF The FEBS Journal 2020
X1INH, an improved next-generation affinity-optimized hydrazonic ligand, attenuates abnormal copper(i)/copper(ii)-α-Syn interactions and affects protein aggregation in a cellular model of synucleinopathy Cukierman DS, Lázaro DF, (...), Rey NA Dalton Transactions 2020
Tipping the Scales: Peptide-Dependent Dysregulation of Neural Circuit Dynamics in Alzheimer’s Disease Harris SS, Wolf F, De Strooper B, Busche MA Neuron 2020
A comparative analysis of the mobility of 45 proteins in the synaptic bouton (Open Access) Reshetniak S, Ußling J, (...), Rizzoli SO EMBO Journal 2020
The Role of Alpha-Synuclein And Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders (Open Access) Morato Torres CA, Wassouf Z, Zafar F, Sastre D, Outeiro TF, Schüle B Preprints 2020
Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids (Open Access) Zafeiriou M, Bao G, (...), Zimmermann W Nature Communications 2020
Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices (Open Access) Imig C, López-Murcia FJ, (...), Cooper BH Neuron 2020
A streamlined pipeline for multiplexed quantitative site-specific N-glycoproteomics (Open Access) Fang P, Ji Y, (...), Urlaub H Nature Communications 2020
Increased expression of myelin-associated genes in frontal cortex of SNCA overexpressing rats and Parkinson's disease patients. (Open Access) Hentrich T, Wassouf Z, (...), Schulze-Hentrich JM Aging-US 2020
Neuropathology of patients with COVID-19 in Germany: a post-mortem case series (Open Access) Matschke J, Lütgehetmann M, (...), Glatzel M Lancet Neurology 2020
Neuroligin-2 dependent conformational activation of Collybistin reconstituted in supported hybrid membranes Schäfer J, Förster L, Mey I, Papadopoulos T, Brose N, Steinem C Journal of Biological Chemistry 2020
From iPS Cells to Rodents and Nonhuman Primates: Filling Gaps in Modeling Parkinson's Disease Outeiro TF, Heutink P, Bezard E, Cenci AM Movement Disorders 2020
Synaptic activity and strength are reflected by changes in the post-synaptic secretory pathway (Open Access) Gürth C, Dankovich TM, Rizzoli SO, D’Este E Scientific Reports 2020
A minimalist model to measure interactions between proteins and synaptic vesicles (Open Access) Perego E, Reshetniak S, (...), Köster S Scientific Reports 2020
The mRNA-binding protein RBM3 regulates activity patterns and local synaptic translation in cultured hippocampal neurons (Open Access) Sertel SM, von Elling-Tammen MS, Rizzoli SO The Journal of Neuroscience 2020
Rho‐Kinase Inhibition by Fasudil Modulates Presynaptic Vesicle Dynamics (Open Access) Saal KA, Warth Pérez Arias C, (...), Lingor P Journal of Neurochemistry 2020
Deep learning–based cell composition analysis from tissue expression profiles (Open Access) Menden K, Marouf M, (...), Bonn S Science Advances 2020
Distinct Mechanisms of Over-Representation of Landmarks and Rewards in the Hippocampus (Open Access) Sato M, Mizuta K, (...), Hayashi Y Cell Reports 2020
A nanobody-based fluorescent reporter reveals human α-synuclein in the cell cytosol (Open Access) Gerdes C, Waal N, (...), Opazo F Nature Communications 2020
Vesicle adhesion in the electrostatic strong-coupling regime studied by time-resolved small-angle X-ray scattering (Open Access) Komorowski K, Schaeper J, (...), Salditt T Soft Matter 2020
SUMOylation controls the neurodevelopmental function of the transcription factor Zbtb20 (Open Access) Ripamonti S, Shomroni O, (...), Tirard M Journal of Neurochemistry 2020
An experimentally generated peptide database increases the sensitivity of XL-MS with complex samples Parfentev I, Schilbach S, Cramer P, Urlaub H Journal of Proteomics 2020
Modeling the Shape of Synaptic Spines by Their Actin Dynamics (Open Access) Bonilla-Quintana M, Wörgötter F, Tetzlaff C, Fauth M Frontiers in Synaptic Neuroscience 2020
The self-organized learning of noisy environmental stimuli requires distinct phases of plasticity (Open Access) Krüppel S, Tetzlaff C Network Neuroscience 2020
Editorial: Protein Misfolding and Spreading Pathology in Neurodegenerative Diseases (Open Access) Lázaro DF, Bellucci A, Brundin P, Outeiro TF Frontiers in Molecular Neuroscience 2020
Realistic in silico generation and augmentation of single-cell RNA-seq data using generative adversarial networks (Open Access) Marouf M, Machart P, (...), Bonn S Nature Communications 2020
White matter integrity requires continuous myelin synthesis at the inner tongue (Open Access) Meschkat M, Steyer AM, (...), Möbius W bioRxiv 2020
Post-translational modifications soften vimentin intermediate filaments (Open Access) Kraxner J, Lorenz C, (...), Köster S Nanoscale 2020
The Coding And Small-Non-Coding Hippocampal Synaptic RNAome (Open Access) Epple R, Krüger D, (...), Fischer A bioRxiv 2020
Local translation in synaptic mitochondria influences synaptic transmission (Open Access) Yousefi R, Fornasiero EF, (...), Pacheu-Grau D bioRxiv 2020
RAB39B is redistributed in dementia with Lewy bodies and is sequestered within aβ plaques and Lewy bodies (Open Access) Koss DJ, Bondarevaite O, (...), Outeiro TF Brain Pathology 2020
The Role of Alpha-Synuclein and Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders (Open Access) Morato Torres CA, Wassouf Z, Zafar F, Sastre D, Outeiro TF, Schüle B International Journal of Molecular Sciences 2020
Spatial clustering of orientation preference in primary visual cortex of the large rodent agouti (Open Access) Ferreiro DN, Conde-Ocazionez SA, (...), Schmidt KE iScience 2020
Quantitative Synaptic Biology: A Perspective on Techniques, Numbers and Expectations (Open Access) Reshetniak S, Fernández-Busnadiego R, Müller M, Rizzoli SO, Tetzlaff C International Journal of Molecular Sciences 2020
A sensory cell diversifies its output by varying Ca 2+ influx‐release coupling among active zones (Open Access) Özçete ÖD, Moser T EMBO Journal 2020
Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo (Open Access) Dominguez-Meijide A, Parrales V, (...), Outeiro TF bioRxiv 2020
Circumvention of common labelling artefacts using secondary nanobodies (Open Access) Sograte-Idrissi S, Schlichthaerle T, (...), Opazo F Nanoscale 2020
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R (Open Access) Dankovich TM, Kaushik R, (...), Rizzoli SO bioRxiv 2020
Correction: Circumvention of common labelling artefacts using secondary nanobodies (Open Access) Sograte-Idrissi S, Schlichthaerle T, (...), Opazo F Nanoscale 2020
Are genetic and idiopathic forms of Parkinson’s disease the same disease? (Open Access) Correia Guedes L, Mestre T, Outeiro TF, Ferreira JJ Journal of Neurochemistry 2019
A practical guide to optimization in X10 expansion microscopy Truckenbrodt S, Sommer C, Rizzoli SO, Danzl JG Nature Protocols 2019
Principles underlying the input-dependent formation and organization of memories (Open Access) Herpich J, Tetzlaff C Network Neuroscience 2019
Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies (Open Access) Szegő ÉM, Dominguez-Meijide A, (...), Outeiro TF Cell Reports 2019
Interrogating Synaptic Architecture: Approaches for Labeling Organelles and Cytoskeleton Components (Open Access) Reshetniak S, Rizzoli SO Frontiers in Synaptic Neuroscience 2019
Deep-learning-based cell composition analysis from tissue expression profiles Menden K, Marouf M, Dalmia A, Heutink P, Bonn S bioRxiv 2019
Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity (Open Access) Carija A, Pinheiro F, (...), Ventura S Redox Biology 2019
A Theoretical Framework to Derive Simple, Firing-Rate-Dependent Mathematical Models of Synaptic Plasticity (Open Access) Lappalainen J, Herpich J, Tetzlaff C Frontiers in Computational Neuroscience 2019
In vitro models of synucleinopathies: informing on molecular mechanisms and protective strategies Marvian AT, Koss DJ, Aliakbari F, Morshedi D, Outeiro TF Journal of Neurochemistry 2019
Neuronal Redox-Imbalance in Rett Syndrome Affects Mitochondria as Well as Cytosol, and Is Accompanied by Intensified Mitochondrial O2 Consumption and ROS Release (Open Access) Can K, Menzfeld C, (...), Müller M Frontiers in Physiology 2019
Translocator Protein Ligand Protects against Neurodegeneration in the MPTP Mouse Model of Parkinsonism Gong J, Szego ÉM, (...), Schneider A The Journal of Neuroscience 2019
SIMS imaging in neurobiology and cell biology (Open Access) Agüi-Gonzalez P, Jähne S, Phan NTN Journal of Analytical Atomic Spectrometry 2019
The Contribution of Iron to Protein Aggregation Disorders in the Central Nervous System (Open Access) Joppe K, Roser A, Maass F, Lingor P Frontiers in Neuroscience 2019
Correlating Synaptic Ultrastructure and Function at the Nanoscale (Open Access) Maus L, Altas B, Rhee J, Brose N, Imig C, Cooper BH bioRxiv 2019
Correlative STED super-resolution light and electron microscopy on resin sections Wurm CA, Schwarz H, Jans DC, Riedel D, Humbel BM, Jakobs S Journal of Physics D-Applied Physics 2019
Deep Learning and Random Forest-Based Augmentation of sRNA Expression Profiles Fiosina J, Fiosins M, Bonn S Lecture Notes in Computer Science 2019
LRRK2, alpha-synuclein, and tau: partners in crime or unfortunate bystanders? (Open Access) Outeiro TF, Harvey K, Dominguez-Meijide A, Gerhardt E Biochemical Society Transactions 2019
Epigenetics of the Synapse in Neurodegeneration (Open Access) Xylaki M, Atzler B, Outeiro TF Current Neurology and Neuroscience Reports 2019
Investigating targets for neuropharmacological intervention by molecular dynamics simulations (Open Access) Rossetti G, Kless A, Lai L, Outeiro TF, Carloni P Biochemical Society Transactions 2019
Live-cell STED nanoscopy of mitochondrial cristae (Open Access) Stephan T, Roesch A, Riedel D, Jakobs S Scientific Reports 2019
Fluorinated nanobodies for targeted molecular imaging of biological samples using nanoscale secondary ion mass spectrometry (Open Access) Kabatas S, Agüi-Gonzalez P, (...), Phan NTN Journal of Analytical Atomic Spectrometry 2019
A 2A R‐induced transcriptional deregulation in astrocytes: An in vitro study Paiva I, Carvalho K, (...), Blum D Glia 2019
Live-cell STED microscopy of mitochondrial cristae (Open Access) Stephan T, Roesch A, Riedel D, Jakobs S bioRxiv 2019
Synuclein Meeting 2019: where we are and where we need to go Outeiro TF, Mestre TA Journal of Neurochemistry 2019
Tagger—A Swiss army knife for multiomics to dissect cell type–specific mechanisms of gene expression in mice (Open Access) Kaczmarczyk L, Bansal V, (...), Jackson WS PLOS Biology 2019
Nanomachinery Organizing Release at Neuronal and Ribbon Synapses (Open Access) Chakrabarti R, Wichmann C International Journal of Molecular Sciences 2019
The self-organized learning of noisy environmental stimuli requires distinct phases of plasticity (Open Access) Krüppel S, Tetzlaff C bioRxiv 2019
The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43 (Open Access) Keihani S, Kluever V, (...), Fornasiero EF Science Advances 2019
Explainable Deep Learning for Augmentation of Small RNA Expression Profiles (Open Access) Fiosina J, Fiosins M, Bonn S Journal of Computational Biology 2019
Explainable Deep Learning for Augmentation of sRNA Expression Profiles (Open Access) Fiosina J, Fiosins M, Bonn S arXiv 2019
Mechanisms of alpha-synuclein toxicity: An update and outlook Brás IC, Xylaki M, Outeiro TF Progress in Brain Research 2019
A mass spectrometry workflow for measuring protein turnover rates in vivo (Open Access) Alevra M, Mandad S, Ischebeck T, Urlaub H, Rizzoli SO, Fornasiero EF Nature Protocols 2019
A combined miRNA–piRNA signature to detect Alzheimer’s disease (Open Access) Jain G, Stuendl A, (...), Fischer A Translational Psychiatry 2019
Seeding variability of different alpha synuclein strains in synucleinopathies Candelise N, Schmitz M, (...), Zerr I Annals of Neurology 2019
Boron‐Containing Probes for Non‐optical High‐Resolution Imaging of Biological Samples (Open Access) Kabatas S, Agüi‐Gonzalez P, (...), Phan NTN Angewandte Chemie-International Edition 2019
Combined Use of Unnatural Amino Acids Enables Dual-Color Super-Resolution Imaging of Proteins via Click Chemistry Saal K, Richter F, Rehling P, Rizzoli SO ACS Nano 2018
Nanobodies reveal an extra-synaptic population of SNAP-25 and Syntaxin 1A in hippocampal neurons (Open Access) Maidorn M, Olichon A, Rizzoli SO, Opazo F mAbs 2018
The role of LRRK2 in cell signalling (Open Access) Harvey K, Outeiro TF Biochemical Society Transactions 2018
Kollaboratives Forschungszentrum (Sonderforschungsbereich, SFB) 1286 „Quantitative Synaptologie“ (Open Access) Schubert K, Rizzoli SO Neuroforum 2018
Circulating miRNAs as Diagnostic Biomarkers for Parkinson’s Disease (Open Access) Roser AE, Caldi Gomes L, Schünemann J, Maass F, Lingor P Frontiers in Neuroscience 2018
Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function Paiva I, Jain G, (...), Outeiro TF Neurobiology of Disease 2018
Membrane binding, internalization, and sorting of alpha-synuclein in the cell (Open Access) Masaracchia C, Hnida M, (...), Outeiro TF Acta Neuropathologica Communications 2018
Robust nanoscopy of a synaptic protein in living mice by organic-fluorophore labeling (Open Access) Masch J, Steffens H, (...), Hell SW Proceedings of the National Academy of Sciences of the United States of America 2018
Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission (Open Access) Truckenbrodt S, Viplav A, (...), Rizzoli SO The EMBO Journal 2018
X10 expansion microscopy enables 25‐nm resolution on conventional microscopes (Open Access) Truckenbrodt S, Maidorn M, Crzan D, Wildhagen H, Kabatas S, Rizzoli SO EMBO reports 2018
Sensing α-Synuclein From the Outside via the Prion Protein: Implications for Neurodegeneration Brás IC, Lopes LV, Outeiro TF Movement Disorders 2018
Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions (Open Access) Fornasiero EF, Mandad S, (...), Rizzoli SO Nature Communications 2018
Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein (Open Access) Pinho R, PaivaI , (...), Outeiro TF Human Molecular Genetics 2018
Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons (Open Access) Pujols J, Peña-Díaz S, (...), Ventura S Proceedings of the National Academy of Sciences of the United States of America 2018
SUMO1-conjugation is altered during normal aging but not by increased amyloid burden (Open Access) Stankova T, Piepkorn L, Bayer TA, Jahn O, Tirard M Aging Cell 2018
WDR1 is a novel EYA3 substrate and its dephosphorylation induces modifications of the cellular actin cytoskeleton (Open Access) Mentel M, Ionescu AE, (...), Szedlacsek SE Scientific Reports 2018
RIM-Binding Protein 2 Promotes a Large Number of CaV1.3 Ca2+-Channels and Contributes to Fast Synaptic Vesicle Replenishment at Hair Cell Active Zones (Open Access) Krinner S, Butola T, Jung S, Wichmann C, Moser T Frontiers in Cellular Neuroscience 2017
Piccolo Promotes Vesicle Replenishment at a Fast Central Auditory Synapse (Open Access) Butola T, Wichmann C, Moser T Frontiers in Synaptic Neuroscience 2017