| Uncovering the molecular link between lead toxicity and Parkinson’s disease | | Shvachiy L, Geraldes V, Outeiro T | Antioxidants & Redox Signaling | 2023 | | |
| Trafficking proteins show limited differences in mobility across different postsynaptic spines | 
| Mougios N, Opazo F, Rizzoli SO, Reshetniak S | iScience | 2023 | | |
| Phase Separation in Biology and Disease; Current Perspectives and Open Questions |
| Boeynaems S, Chong S, (...), Kriwacki R | Journal of Molecular Biology | 2023 | | |
| Neurodegenerative disease of the brain: a survey of interdisciplinary approaches |
| Davenport F, Gallacher J, (...), Zetterberg H | Journal of The Royal Society Interface | 2023 | | |
| Deep learning enables fast, gentle STED microscopy |
| Ebrahimi V, Stephan T, (...), Han KY | bioRxiv | 2023 | | |
| Condensate biology of synaptic vesicle clusters |
| Sansevrino R, Hoffmann C, Milovanovic D | Trends in Neurosciences | 2023 | | |
| A versatile Synaptotagmin-1 nanobody provides perturbation-free live synaptic imaging and low linkage-error in super-resolution microscopy |
| Villa Real KQZ, Mougios N, (...), Opazo F | bioRxiv | 2023 | | |
| Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF |
| Antoniou A, Auderset L, (...), Schneider A | Cell Reports | 2023 | | |
| Alpha-synuclein oligomers activate nuclear factor of activated T-cells (NFAT) modulating apoptosis and synaptic homeostasis |
| Sant'Anna R, Robbs BK, (...), Foguel D | bioRxiv | 2023 | | |
| Conserved reduction of m6A RNA modifications during aging and neurodegeneration is linked to changes in synaptic transcripts |
| Castro-Hernández R, Berulava T, (...), Fischer A | Proceedings of the National Academy of Sciences of the United States of America | 2023 | | |
| The multifaceted mitochondrial OXA insertase |
| Homberg B, Rehling P, Cruz-Zaragoza LD | Trends in Cell Biology | 2023 | | |
| Intermittent Lead Exposure Induces Behavioral and Cardiovascular Alterations Associated with Neuroinflammation |
| Shvachiy L, Amaro-Leal A, Outeiro TF, Rocha I, Geraldes V | Cells | 2023 | | |
| Characterizing the differential distribution and targets of Sumo1 and Sumo2 in the mouse brain |
| Suk TR, Nguyen TT, (...), Rousseaux MW | iScience | 2023 | | |
| Impact of Phosphorylation on alpha-Synuclein Structural Determinants |
| Dorn AE, de Bruyn E, (...), Carloni P | bioRxiv | 2023 | | |
| Reverse-time analysis uncovers universality classes in directional biological dynamics |
| Lenner N, Eule S, Großhans J, Wolf F | arXiv | 2023 | | |
| Towards a Biological Definition of Parkinson’s Disease |
| Höglinger GU, Adler CH, (...), Lang AE | Preprints | 2023 | | |
| Expansion-enhanced super-resolution radial fluctuations enable nanoscale molecular profiling of pathology specimens |
| Kylies D, Zimmermann M, (...), Puelles VG | Nature Nanotechnology | 2023 | | |
| Reverse-time analysis and boundary classification of directional biological dynamics with multiplicative noise |
| Lenner N, Häring M, Eule S, Großhans J, Wolf F | arXiv | 2023 | | |
| Chemical Synthesis of Alpha‐Synuclein Proteins via Solid‐Phase Peptide Synthesis and Native Chemical Ligation |
| Gatzemeier LM, Meyer F, Diederichsen U, Outeiro TF | Chemistry-A European Journal | 2023 | | |
| A novel miR-99b-5p-Zbp1 pathway in microglia contributes to the pathogenesis of schizophrenia |
| Kaurani L, Islam MR, (...), Fischer A | bioRxiv | 2023 | | |
| Prion-like α-synuclein pathology in the brain of infants with Krabbe disease |
| Hatton C, Ghanem SS, (...), Erskine D | Brain | 2022 | | |
| Signals from the interface: protein nanoclusters stabilize biomolecular condensates |
| Hoffmann C, Rankovic B, Milovanovic D | Signal Transduct Target Ther | 2022 | | |
| Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation |
| Torres-Garcia L, P. Domingues JM, (...), Li J | Scientific Reports | 2022 | | |
| Identification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes |
| Chang HF, Schirra C, (...), Rettig J | Nature Communications | 2022 | | |
| Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3 | | Upmanyu N, Jin J, (...), Sambandan S | Neuron | 2022 | | |
| Methods for multiscale structural and functional analysis of the mammalian cochlea | | Vogl C, Neef J, Wichmann C | Molecular and Cellular Neuroscience | 2022 | | |
| DiSCERN - Deep Single Cell Expression ReconstructioN for improved cell clustering and cell subtype and state detection |
| Hausmann F, Ergen-Behr C, (...), Bonn S | bioRxiv | 2022 | | |
| Extracellular alpha-synuclein: Sensors, receptors, and responses |
| Domingues R, Sant’Anna R, da Fonseca ACC, Robbs BK, Foguel D, Outeiro TF | Neurobiology of Disease | 2022 | | |
| The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains |
| Peña-Díaz S, Pujols J, (...), Ventura S | Journal of Biological Chemistry | 2022 | | |
| Extracellular Matrix Recycling as a Novel Plasticity Mechanism With a Potential Role in Disease |
| Dankovich TM, Rizzoli SO | Frontiers in Cellular Neuroscience | 2022 | | |
| The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible |
| Cassotta M | ALTEX-Alternatives to Animal Experimentation | 2022 | | |
| Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses |
| Chakrabarti R, Jaime Tobón LM, (...), Wichmann C | bioRxiv | 2022 | | |
| Optimal precision and accuracy in 4Pi-STORM using dynamic spline PSF models |
| Bates M, Keller-Findeisen J, (...), Hell SW | Nature Methods | 2022 | | |
| An iodine-containing probe as a tool for molecular detection in secondary ion mass spectrometry |
| Kabatas Glowacki S, Agüi-Gonzalez P, (...), Rizzoli SO | Chemical Communications | 2022 | | |
| Aromaticity at position 39 in α‐synuclein: A modulator of amyloid fibril assembly and membrane‐bound conformations |
| Buratti FA, Boeffinger N, (...), Fernández CO | Protein Science | 2022 | | |
| Resolving the molecular architecture of the photoreceptor active zone with 3D-MINFLUX |
| Grabner CP, Jansen I, (...), Moser T | Science Advances | 2022 | | |
| JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species |
| Santos CC, Cardim-Pires TR, (...), Silva VDA | Neurotoxicity Research | 2022 | | |
| Ectosomes and exosomes modulate neuronal spontaneous activity | | Brás IC, Khani MH, (...), Outeiro TF | Journal of Proteomics | 2022 | | |
| Glycation modulates glutamatergic signaling and exacerbates Parkinson’s disease-like phenotypes |
| Chegão A, Guarda M, (...), Vicente Miranda H | npj Parkinson's Disease | 2022 | | |
| Extracellular vesicles derived from the choroid plexus trigger the differentiation of neural stem cells |
| Ditte Z, Silbern I, Ditte P, Urlaub H, Eichele G | Journal of Extracellular Vesicles | 2022 | | |
| Focused ion beam‐scanning electron microscopy links pathological myelin outfoldings to axonal changes in mice lacking Plp1 or Mag |
| Steyer AM, Buscham TJ, (...), Werner HB | Glia | 2022 | | |
| Where is the error? Hierarchical predictive coding through dendritic error computation |
| Mikulasch FA, Rudelt L, Wibral M, Priesemann V | Trends in Neurosciences | 2022 | | |
| ERR2 and ERR3 promote the development of gamma motor neuron functional properties required for proprioceptive movement control |
| Khan MN, Cherukuri P, (...), Marquardt T | PLOS Biology | 2022 | | |
| Abstract: A10.00009 : The role of protein constriction in the fission of membrane tubes |
| Spencer RK, Müller M | APS March Meeting 2023 | 2022 | | |
| Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies |
| Koss DJ, Erskine D, (...), Outeiro TF | Acta Neuropathologica Communications | 2022 | | |
| Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses |
| Chakrabarti R, Jaime Tobón LM, (...), Wichmann C | eLife | 2022 | | |
| Endogenous Levels of Alpha-Synuclein Modulate Seeding and Aggregation in Cultured Cells |
| Vasili E, Dominguez-Meijide A, (...), Outeiro TF | Molecular Neurobiology | 2022 | | |
| Alpha-synuclein overexpression induces epigenomic dysregulation of glutamate signaling and locomotor pathways |
| Schaffner SL, Wassouf Z, (...), Kobor MS | Human Molecular Genetics | 2022 | | |
| Age-dependent structural reorganization of utricular ribbon synapses |
| Michanski S, Henneck T, (...), Wichmann C | bioRxiv | 2022 | | |
| Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity | | Brás IC, Khani MH, (...), Outeiro TF | Journal of Parkinson's Disease | 2022 | | |
| Conserved reduction of m<sup>6</sup>A marks during aging and neurodegeneration is linked to altered translation of synaptic transcripts |
| Castro-Hernández R, Berulava T, (...), Fischer A | bioRxiv | 2022 | | |
| Alpha-Synuclein Antibody Characterization: Why Semantics Matters |
| Outeiro TF | Molecular Neurobiology | 2021 | | |
| Non-negative Matrix Factorization as a Tool to Distinguish Between Synaptic Vesicles in Different Functional States | | Neher E, Taschenberger H | Neuroscience | 2021 | | |
| Exploring early time points of vimentin assembly in flow by fluorescence fluctuation spectroscopy | | Perego E, Köster S | Lab on a Chip | 2021 | | |
| NanoSIMS observations of mouse retinal cells reveal strict metabolic controls on nitrogen turnover |
| Bonnin EA, Fornasiero EF, Lange F, Turck CW, Rizzoli SO | BMC Molecular and Cell Biology | 2021 | | |
| Challenges facing quantitative large-scale optical super-resolution, and some simple solutions |
| Dankovich TM, Rizzoli SO | iScience | 2021 | | |
| Intranuclear immunostaining-based FACS protocol from embryonic cortical tissue |
| Sakib MS, Sokpor G, Nguyen HP, Fischer A, Tuoc T | STAR Protocols | 2021 | | |
| Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders |
| Erskine D, Koss D, Korolchuk VI, Outeiro TF, Attems J, McKeith I | Acta Neuropathologica | 2021 | | |
| Sulthiame impairs mitochondrial function in vitro and may trigger onset of visual loss in Leber hereditary optic neuropathy |
| Reinert M, Pacheu-Grau D, (...), Brockmann K | Orphanet Journal of Rare Diseases | 2021 | | |
| Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation |
| Jafari M, Schumacher A, (...), Kerschensteiner M | Nature Neuroscience | 2021 | | |
| Hippocampal neurons respond to brain activity with functional hypoxia |
| Butt UJ, Steixner-Kumar AA, (...), Ehrenreich H | Molecular Psychiatry | 2021 | | |
| Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo |
| Dominguez-Meijide A, Parrales V, (...), Outeiro TF | Neurobiology of Disease | 2021 | | |
| Protein phosphorylation in depolarized synaptosomes: Dissecting primary effects of calcium from synaptic vesicle cycling |
| Silbern I, Pan K, (...), Jahn R | Molecular & Cellular Proteomics | 2021 | | |
| Monitoring mitochondrial translation in living cells |
| Yousefi R, Fornasiero EF, (...), Pacheu‐Grau D | EMBO Reports | 2021 | | |
| Reproducing asymmetrical spine shape fluctuations in a model of actin dynamics predicts self-organized criticality |
| Bonilla-Quintana M, Wörgötter F, D’Este E, Tetzlaff C, Fauth M | Scientific Reports | 2021 | | |
| Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients |
| Zhao Y, Kilian C, (...), Krebs CF | Science Immunology | 2021 | | |
| The Coding and Small Non-coding Hippocampal Synaptic RNAome |
| Epple R, Krüger D, (...), Fischer A | Molecular Neurobiology | 2021 | | |
| Cofilin pathology is a new player on α-synuclein-induced spine impairment in models of hippocampal synucleinopathy |
| Oliveira da Silva MI, Santejo M, (...), Liz M | bioRxiv | 2021 | | |
| Ultrastructural maturation of endbulb of Held active zones comparing wild-type and otoferlin-deficient mice |
| Hintze A, Gültas M, Semmelhack EA, Wichmann C | iScience | 2021 | | |
| The vesicle cluster as a major organizer of synaptic composition in the short-term and long-term |
| Reshetniak S, Rizzoli SO | Current Opinion in Cell Biology | 2021 | | |
| RIM-Binding Proteins Are Required for Normal Sound-Encoding at Afferent Inner Hair Cell Synapses |
| Krinner S, Predoehl F, Burfeind D, Vogl C, Moser T | Frontiers in Molecular Neuroscience | 2021 | | |
| The effect of polydispersity, shape fluctuations and curvature on small unilamellar vesicle small-angle X-ray scattering curves |
| Chappa V, Smirnova Y, Komorowski K, Müller M, Salditt T | Journal of Applied Crystallography | 2021 | | |
| Synapsin Condensates Recruit alpha-Synuclein |
| Hoffmann C, Sansevrino R, (...), Milovanovic D | Journal of Molecular Biology | 2021 | | |
| Presynaptic activity and protein turnover are correlated at the single-synapse level |
| Jähne S, Mikulasch F, (...), Priesemann V | Cell Reports | 2021 | | |
| Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex |
| Ulmke PA, Sakib MS, (...), Tuoc T | Stem Cell Reports | 2021 | | |
| Secondary Ion Mass Spectrometry Imaging Reveals Changes in the Lipid Structure of the Plasma Membranes of Hippocampal Neurons following Drugs Affecting Neuronal Activity |
| Agüi-Gonzalez P, Guobin B, Gomes de Castro MA, Rizzoli SO, Phan NTN | ACS Chemical Neuroscience | 2021 | | |
| Gold-conjugated Nanobodies for Targeted Imaging using High-resolution Secondary Ion Mass Spectrometry |
| Agüi-Gonzalez P, Dankovich TM, Opazo F, Rizzoli SO, Phan NT | Preprints | 2021 | | |
| Alpha-synuclein induces epigenomic dysregulation of glutamate signaling and locomotor pathways |
| Schaffner SL, Wassouf Z, (...), Kobor MS | bioRxiv | 2021 | | |
| Super-resolution microscopy informs on the molecular architecture of alpha-synuclein inclusions in model systems and in the human brain |
| Weish P, Lazaro DF, (...), Outeiro TF | bioRxiv | 2021 | | |
| RIM-Binding Protein 2 organizes Ca2+ channel topography and regulates release probability and vesicle replenishment at a fast central synapse |
| Butola T, Alvanos T, (...), Moser T | bioRxiv | 2021 | | |
| Dysfunction of RAB39B‐Mediated Vesicular Trafficking in Lewy Body Diseases |
| Koss DJ, Campesan S, Giorgini F, Outeiro TF | Movement Disorders | 2021 | | |
| A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines |
| Helm MS, Dankovich TM, (...), Rizzoli SO | Nature Neuroscience | 2021 | | |
| Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein |
| Martinez Hernandez A, Silbern I, (...), Eichele G | Frontiers in Neuroscience | 2021 | | |
| Allosteric transcription stimulation by RNA polymerase II super elongation complex | | Chen Y, Vos SM, Dienemann C, Ninov M, Urlaub H, Cramer P | Molecular Cell | 2021 | | |
| Common molecular mechanisms underlie the transfer of alpha-synuclein, Tau and huntingtin and modulate spontaneous activity in neuronal cells |
| Brás IC, Khani MH, (...), Outeiro TF | bioRxiv | 2021 | | |
| Surface tension and viscosity of protein condensates quantified by micropipette aspiration |
| Wang H, Kelley FM, Milovanovic D, Schuster BS, Shi Z | Biophysical Reports | 2021 | | |
| Cellular Prion Protein Mediates α‐Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo |
| Thom T, Schmitz M, (...), Zerr I | Movement Disorders | 2021 | | |
| Differences in synaptic vesicle pool behavior between male and female hippocampal cultured neurons |
| Sertel SM, Blumenstein W, Mandad S, Shomroni O, Salinas G, Rizzoli SO | Scientific Reports | 2021 | | |
| Tubular microdomains of Rab7-endosomes retrieve TrkA, a mechanism disrupted in Charcot-Marie-Tooth 2B | | Markworth R, Dambeck V, (...), Burk K | Journal of Cell Science | 2021 | | |
| Management of Metadata Types in Basic Cardiological Research |
| Kusch H, Kossen R, (...), Nussbeck SY | Studies in Health Technology and Informatics | 2021 | | |
| Bias-invariant RNA-sequencing metadata annotation |
| Wartmann H, Heins S, Kloiber K, Bonn S | Gigascience | 2021 | | |
| Principles of brain aging: Status and challenges of modeling human molecular changes in mice | | Kluever V, Fornasiero EF | Ageing Research Reviews | 2021 | | |
| GMDS2021 ePoster and video teaser for DOI 10.3205/21gmds072 |
| Kusch H, Bauer CR, (...), Sax U | Göttingen Research Online / Data | 2021 | | |
| Exercise as a model to identify microRNAs linked to human cognition: a role for microRNA-409 and microRNA-501 |
| Goldberg M, Islam MR, (...), Fischer A | Translational Psychiatry | 2021 | | |
| The mammalian rod synaptic ribbon is essential for Cav channel facilitation and ultrafast synaptic vesicle fusion |
| Grabner CP, Moser T | eLife | 2021 | | |
| Munc13-1 is a Ca2+-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission |
| Lipstein N, Chang S, (...), Brose N | Neuron | 2021 | | |
| Heterogeneity of glutamatergic synapses: cellular mechanisms and network consequences |
| Wichmann C, Kuner T | Physiological Reviews | 2021 | | |
| Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy |
| Kettwig M, Ternka K, (...), Gärtner J | Nature Communications | 2021 | | |
| Three-dimensional virtual histology of the cerebral cortex based on phase-contrast X-ray tomography |
| Eckermann M, van der Meer F, (...), Salditt T | Biomedical Optics Express | 2021 | | |
| Punctuated evolution of visual cortical circuits? Evidence from the large rodent Dasyprocta leporina, and the tiny primate Microcebus murinus |
| Schmidt KE, Wolf F | Current Opinion in Neurobiology | 2021 | | |
| Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron‐enriched genes |
| Michurina A, Sakib MS, (...), Fischer A | The EMBO Journal | 2021 | | |
| Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R |
| Dankovich TM, Kaushik R, (...), Rizzoli SO | Nature Communications | 2021 | | |
| Endogenous Levels of Alpha-synuclein Modulate Seeding and Aggregation in Cultured Cells |
| Vasili E, Dominguez-Meijide A, (...), Outeiro T | Researchsquare | 2021 | | |
| RIM-Binding Protein 2 Organizes Ca2+ Channel Topography and Regulates Release Probability and Vesicle Replenishment at a Fast Central Synapse |
| Butola T, Alvanos T, (...), Moser T | The Journal of Neuroscience | 2021 | | |
| A microRNA signature that correlates with cognition and is a target against cognitive decline |
| Islam MR, Kaurani L, (...), Fischer A | EMBO Molecular Medicine | 2021 | | |
| Conditional Loss of BAF (mSWI/SNF) Scaffolding Subunits Affects Specification and Proliferation of Oligodendrocyte Precursors in Developing Mouse Forebrain |
| Abbas E, Hassan MA, (...), Tuoc T | Frontiers in Cell and Developmental Biology | 2021 | | |
| Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease |
| Oliveira LMA, Gasser T, (...), Outeiro TF | npj Parkinson's Disease | 2021 | | |
| Co-localization of different neurotransmitter transporters on synaptic vesicles is sparse except of VGLUT1 and ZnT3 |
| Upmanyu N, Jin J, (...), Sambandan S | bioRxiv | 2021 | | |
| Monitoring Alpha-Synuclein – Tau Interactions In Vitro and In Vivo Using Bimolecular Fluorescence Complementation |
| Torres-Garcia L, Domingues JM, (...), Li J | Researchsquare | 2021 | | |
| Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies |
| Koss DJ, Erskine D, (...), Outeiro TF | bioRxiv | 2021 | | |
| Resolving the molecular architecture of the photoreceptor active zone by MINFLUX nanoscopy |
| Grabner CP, Jansen I, (...), Moser T | bioRxiv | 2021 | | |
| Gold-Conjugated Nanobodies for Targeted Imaging Using High-Resolution Secondary Ion Mass Spectrometry |
| Agüi-Gonzalez P, Dankovich TM, Rizzoli SO, Phan NTN | Nanomaterials | 2021 | | |
| Kinetic coupling of the respiratory chain with ATP synthase, but not proton gradients, drives ATP production in cristae membranes | | Toth A, Meyrat A, (...), Ott M | Proceedings of the National Academy of Sciences of the United States of America | 2020 | | |
| MINFLUX nanoscopy delivers 3D multicolor nanometer resolution in cells | | Gwosch KC, Pape JK, (...), Hell SW | Nature Methods | 2020 | | |
| Leaflet-dependent distribution of PtdIns[4,5]P2 in supported model membranes | | Schäfer J, Nehls J, Schön M, Mey IP, Steinem C | Langmuir | 2020 | | |
| Synucleinopathies: Where we are and where we need to go |
| Brás IC, Dominguez‐Meijide A, (...), Outeiro TF | Journal of Neurochemistry | 2020 | | |
| Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors | | Luo L, Ambrozkiewicz MC, (...), Craig AM | Neuron | 2020 | | |
| Light Microscopy of Mitochondria at the Nanoscale | | Jakobs S, Stephan T, Ilgen P, Brüser C | Annual Review of Biophysics | 2020 | | |
| Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses |
| Maus L, Lee C, (...), Cooper BH | Cell Reports | 2020 | | |
| Protein trapping leads to altered synaptic proteostasis in synucleinopathies |
| Santos PI, Outeiro TF | The FEBS Journal | 2020 | | |
| X1INH, an improved next-generation affinity-optimized hydrazonic ligand, attenuates abnormal copper(i)/copper(ii)-α-Syn interactions and affects protein aggregation in a cellular model of synucleinopathy | | Cukierman DS, Lázaro DF, (...), Rey NA | Dalton Transactions | 2020 | | |
| Tipping the Scales: Peptide-Dependent Dysregulation of Neural Circuit Dynamics in Alzheimer’s Disease | | Harris SS, Wolf F, De Strooper B, Busche MA | Neuron | 2020 | | |
| A comparative analysis of the mobility of 45 proteins in the synaptic bouton |
| Reshetniak S, Ußling J, (...), Rizzoli SO | EMBO Journal | 2020 | | |
| The Role of Alpha-Synuclein And Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders |
| Morato Torres CA, Wassouf Z, Zafar F, Sastre D, Outeiro TF, Schüle B | Preprints | 2020 | | |
| Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids |
| Zafeiriou M, Bao G, (...), Zimmermann W | Nature Communications | 2020 | | |
| Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices |
| Imig C, López-Murcia FJ, (...), Cooper BH | Neuron | 2020 | | |
| A streamlined pipeline for multiplexed quantitative site-specific N-glycoproteomics |
| Fang P, Ji Y, (...), Urlaub H | Nature Communications | 2020 | | |
| Increased expression of myelin-associated genes in frontal cortex of <i>SNCA</i> overexpressing rats and Parkinson's disease patients. |
| Hentrich T, Wassouf Z, (...), Schulze-Hentrich JM | Aging-US | 2020 | | |
| Neuropathology of patients with COVID-19 in Germany: a post-mortem case series |
| Matschke J, Lütgehetmann M, (...), Glatzel M | Lancet Neurology | 2020 | | |
| Neuroligin-2 dependent conformational activation of Collybistin reconstituted in supported hybrid membranes | | Schäfer J, Förster L, Mey I, Papadopoulos T, Brose N, Steinem C | Journal of Biological Chemistry | 2020 | | |
| From iPS Cells to Rodents and Nonhuman Primates: Filling Gaps in Modeling Parkinson's Disease | | Outeiro TF, Heutink P, Bezard E, Cenci AM | Movement Disorders | 2020 | | |
| Synaptic activity and strength are reflected by changes in the post-synaptic secretory pathway |
| Gürth C, Dankovich TM, Rizzoli SO, D’Este E | Scientific Reports | 2020 | | |
| A minimalist model to measure interactions between proteins and synaptic vesicles |
| Perego E, Reshetniak S, (...), Köster S | Scientific Reports | 2020 | | |
| The mRNA-binding protein RBM3 regulates activity patterns and local synaptic translation in cultured hippocampal neurons |
| Sertel SM, von Elling-Tammen MS, Rizzoli SO | The Journal of Neuroscience | 2020 | | |
| Rho‐Kinase Inhibition by Fasudil Modulates Presynaptic Vesicle Dynamics |
| Saal KA, Warth Pérez Arias C, (...), Lingor P | Journal of Neurochemistry | 2020 | | |
| Deep learning–based cell composition analysis from tissue expression profiles |
| Menden K, Marouf M, (...), Bonn S | Science Advances | 2020 | | |
| Distinct Mechanisms of Over-Representation of Landmarks and Rewards in the Hippocampus |
| Sato M, Mizuta K, (...), Hayashi Y | Cell Reports | 2020 | | |
| A nanobody-based fluorescent reporter reveals human α-synuclein in the cell cytosol |
| Gerdes C, Waal N, (...), Opazo F | Nature Communications | 2020 | | |
| Vesicle adhesion in the electrostatic strong-coupling regime studied by time-resolved small-angle X-ray scattering |
| Komorowski K, Schaeper J, (...), Salditt T | Soft Matter | 2020 | | |
| SUMOylation controls the neurodevelopmental function of the transcription factor Zbtb20 |
| Ripamonti S, Shomroni O, (...), Tirard M | Journal of Neurochemistry | 2020 | | |
| An experimentally generated peptide database increases the sensitivity of XL-MS with complex samples | | Parfentev I, Schilbach S, Cramer P, Urlaub H | Journal of Proteomics | 2020 | | |
| Modeling the Shape of Synaptic Spines by Their Actin Dynamics |
| Bonilla-Quintana M, Wörgötter F, Tetzlaff C, Fauth M | Frontiers in Synaptic Neuroscience | 2020 | | |
| The self-organized learning of noisy environmental stimuli requires distinct phases of plasticity |
| Krüppel S, Tetzlaff C | Network Neuroscience | 2020 | | |
| Editorial: Protein Misfolding and Spreading Pathology in Neurodegenerative Diseases |
| Lázaro DF, Bellucci A, Brundin P, Outeiro TF | Frontiers in Molecular Neuroscience | 2020 | | |
| Realistic in silico generation and augmentation of single-cell RNA-seq data using generative adversarial networks |
| Marouf M, Machart P, (...), Bonn S | Nature Communications | 2020 | | |
| Post-translational modifications soften vimentin intermediate filaments |
| Kraxner J, Lorenz C, (...), Köster S | Nanoscale | 2020 | | |
| The Coding And Small-Non-Coding Hippocampal Synaptic RNAome |
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| Local translation in synaptic mitochondria influences synaptic transmission |
| Yousefi R, Fornasiero EF, (...), Pacheu-Grau D | bioRxiv | 2020 | | |
| RAB39B is redistributed in dementia with Lewy bodies and is sequestered within aβ plaques and Lewy bodies |
| Koss DJ, Bondarevaite O, (...), Outeiro TF | Brain Pathology | 2020 | | |
| The Role of Alpha-Synuclein and Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders |
| Morato Torres CA, Wassouf Z, Zafar F, Sastre D, Outeiro TF, Schüle B | International Journal of Molecular Sciences | 2020 | | |
| Quantitative Synaptic Biology: A Perspective on Techniques, Numbers and Expectations |
| Reshetniak S, Fernández-Busnadiego R, Müller M, Rizzoli SO, Tetzlaff C | International Journal of Molecular Sciences | 2020 | | |
| Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo |
| Dominguez-Meijide A, Parrales V, (...), Outeiro TF | bioRxiv | 2020 | | |
| Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R |
| Dankovich TM, Kaushik R, (...), Rizzoli SO | bioRxiv | 2020 | | |
| Are genetic and idiopathic forms of Parkinson’s disease the same disease? |
| Correia Guedes L, Mestre T, Outeiro TF, Ferreira JJ | Journal of Neurochemistry | 2019 | | |
| A practical guide to optimization in X10 expansion microscopy | | Truckenbrodt S, Sommer C, Rizzoli SO, Danzl JG | Nature Protocols | 2019 | | |
| Principles underlying the input-dependent formation and organization of memories |
| Herpich J, Tetzlaff C | Network Neuroscience | 2019 | | |
| Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies |
| Szegő ÉM, Dominguez-Meijide A, (...), Outeiro TF | Cell Reports | 2019 | | |
| Interrogating Synaptic Architecture: Approaches for Labeling Organelles and Cytoskeleton Components |
| Reshetniak S, Rizzoli SO | Frontiers in Synaptic Neuroscience | 2019 | | |
| Deep-learning-based cell composition analysis from tissue expression profiles | | Menden K, Marouf M, Dalmia A, Heutink P, Bonn S | bioRxiv | 2019 | | |
| Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity |
| Carija A, Pinheiro F, (...), Ventura S | Redox Biology | 2019 | | |
| A Theoretical Framework to Derive Simple, Firing-Rate-Dependent Mathematical Models of Synaptic Plasticity |
| Lappalainen J, Herpich J, Tetzlaff C | Frontiers in Computational Neuroscience | 2019 | | |
| In vitro models of synucleinopathies: informing on molecular mechanisms and protective strategies | | Marvian AT, Koss DJ, Aliakbari F, Morshedi D, Outeiro TF | Journal of Neurochemistry | 2019 | | |
| Neuronal Redox-Imbalance in Rett Syndrome Affects Mitochondria as Well as Cytosol, and Is Accompanied by Intensified Mitochondrial O2 Consumption and ROS Release |
| Can K, Menzfeld C, (...), Müller M | Frontiers in Physiology | 2019 | | |
| Translocator Protein Ligand Protects against Neurodegeneration in the MPTP Mouse Model of Parkinsonism | | Gong J, Szego ÉM, (...), Schneider A | The Journal of Neuroscience | 2019 | | |
| SIMS imaging in neurobiology and cell biology |
| Agüi-Gonzalez P, Jähne S, Phan NTN | Journal of Analytical Atomic Spectrometry | 2019 | | |
| The Contribution of Iron to Protein Aggregation Disorders in the Central Nervous System |
| Joppe K, Roser A, Maass F, Lingor P | Frontiers in Neuroscience | 2019 | | |
| Correlating Synaptic Ultrastructure and Function at the Nanoscale |
| Maus L, Altas B, Rhee J, Brose N, Imig C, Cooper BH | bioRxiv | 2019 | | |
| Correlative STED super-resolution light and electron microscopy on resin sections | | Wurm CA, Schwarz H, Jans DC, Riedel D, Humbel BM, Jakobs S | Journal of Physics D-Applied Physics | 2019 | | |
| Deep Learning and Random Forest-Based Augmentation of sRNA Expression Profiles | | Fiosina J, Fiosins M, Bonn S | Lecture Notes in Computer Science | 2019 | | |
| LRRK2, alpha-synuclein, and tau: partners in crime or unfortunate bystanders? |
| Outeiro TF, Harvey K, Dominguez-Meijide A, Gerhardt E | Biochemical Society Transactions | 2019 | | |
| Epigenetics of the Synapse in Neurodegeneration |
| Xylaki M, Atzler B, Outeiro TF | Current Neurology and Neuroscience Reports | 2019 | | |
| Investigating targets for neuropharmacological intervention by molecular dynamics simulations |
| Rossetti G, Kless A, Lai L, Outeiro TF, Carloni P | Biochemical Society Transactions | 2019 | | |
| Live-cell STED nanoscopy of mitochondrial cristae |
| Stephan T, Roesch A, Riedel D, Jakobs S | Scientific Reports | 2019 | | |
| Fluorinated nanobodies for targeted molecular imaging of biological samples using nanoscale secondary ion mass spectrometry |
| Kabatas S, Agüi-Gonzalez P, (...), Phan NTN | Journal of Analytical Atomic Spectrometry | 2019 | | |
| A 2A R‐induced transcriptional deregulation in astrocytes: An in vitro study | | Paiva I, Carvalho K, (...), Blum D | Glia | 2019 | | |
| Live-cell STED microscopy of mitochondrial cristae |
| Stephan T, Roesch A, Riedel D, Jakobs S | bioRxiv | 2019 | | |
| Synuclein Meeting 2019: where we are and where we need to go | | Outeiro TF, Mestre TA | Journal of Neurochemistry | 2019 | | |
| Tagger—A Swiss army knife for multiomics to dissect cell type–specific mechanisms of gene expression in mice |
| Kaczmarczyk L, Bansal V, (...), Jackson WS | PLOS Biology | 2019 | | |
| Nanomachinery Organizing Release at Neuronal and Ribbon Synapses |
| Chakrabarti R, Wichmann C | International Journal of Molecular Sciences | 2019 | | |
| The self-organized learning of noisy environmental stimuli requires distinct phases of plasticity |
| Krüppel S, Tetzlaff C | bioRxiv | 2019 | | |
| The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43 |
| Keihani S, Kluever V, (...), Fornasiero EF | Science Advances | 2019 | | |
| Explainable Deep Learning for Augmentation of Small RNA Expression Profiles |
| Fiosina J, Fiosins M, Bonn S | Journal of Computational Biology | 2019 | | |
| Explainable Deep Learning for Augmentation of sRNA Expression Profiles |
| Fiosina J, Fiosins M, Bonn S | arXiv | 2019 | | |
| Mechanisms of alpha-synuclein toxicity: An update and outlook | | Brás IC, Xylaki M, Outeiro TF | Progress in Brain Research | 2019 | | |
| A mass spectrometry workflow for measuring protein turnover rates in vivo |
| Alevra M, Mandad S, Ischebeck T, Urlaub H, Rizzoli SO, Fornasiero EF | Nature Protocols | 2019 | | |
| A combined miRNA–piRNA signature to detect Alzheimer’s disease |
| Jain G, Stuendl A, (...), Fischer A | Translational Psychiatry | 2019 | | |
| Seeding variability of different alpha synuclein strains in synucleinopathies | | Candelise N, Schmitz M, (...), Zerr I | Annals of Neurology | 2019 | | |
| Boron‐Containing Probes for Non‐optical High‐Resolution Imaging of Biological Samples |
| Kabatas S, Agüi‐Gonzalez P, (...), Phan NTN | Angewandte Chemie-International Edition | 2019 | | |
| Combined Use of Unnatural Amino Acids Enables Dual-Color Super-Resolution Imaging of Proteins via Click Chemistry | | Saal K, Richter F, Rehling P, Rizzoli SO | ACS Nano | 2018 | | |
| Nanobodies reveal an extra-synaptic population of SNAP-25 and Syntaxin 1A in hippocampal neurons |
| Maidorn M, Olichon A, Rizzoli SO, Opazo F | mAbs | 2018 | | |
| The role of LRRK2 in cell signalling |
| Harvey K, Outeiro TF | Biochemical Society Transactions | 2018 | | |
| Kollaboratives Forschungszentrum (Sonderforschungsbereich, SFB) 1286 „Quantitative Synaptologie“ |
| Schubert K, Rizzoli SO | Neuroforum | 2018 | | |
| Circulating miRNAs as Diagnostic Biomarkers for Parkinson’s Disease |
| Roser AE, Caldi Gomes L, Schünemann J, Maass F, Lingor P | Frontiers in Neuroscience | 2018 | | |
| Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function | | Paiva I, Jain G, (...), Outeiro TF | Neurobiology of Disease | 2018 | | |
| Membrane binding, internalization, and sorting of alpha-synuclein in the cell |
| Masaracchia C, Hnida M, (...), Outeiro TF | Acta Neuropathologica Communications | 2018 | | |
| Robust nanoscopy of a synaptic protein in living mice by organic-fluorophore labeling |
| Masch J, Steffens H, (...), Hell SW | Proceedings of the National Academy of Sciences of the United States of America | 2018 | | |
| Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission |
| Truckenbrodt S, Viplav A, (...), Rizzoli SO | The EMBO Journal | 2018 | | |
| X10 expansion microscopy enables 25‐nm resolution on conventional microscopes |
| Truckenbrodt S, Maidorn M, Crzan D, Wildhagen H, Kabatas S, Rizzoli SO | EMBO reports | 2018 | | |
| Sensing α-Synuclein From the Outside via the Prion Protein: Implications for Neurodegeneration | | Brás IC, Lopes LV, Outeiro TF | Movement Disorders | 2018 | | |
| Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions |
| Fornasiero EF, Mandad S, (...), Rizzoli SO | Nature Communications | 2018 | | |
| Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein |
| Pinho R, PaivaI , (...), Outeiro TF | Human Molecular Genetics | 2018 | | |
| Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons |
| Pujols J, Peña-Díaz S, (...), Ventura S | Proceedings of the National Academy of Sciences of the United States of America | 2018 | | |
| SUMO1-conjugation is altered during normal aging but not by increased amyloid burden |
| Stankova T, Piepkorn L, Bayer TA, Jahn O, Tirard M | Aging Cell | 2018 | | |
| WDR1 is a novel EYA3 substrate and its dephosphorylation induces modifications of the cellular actin cytoskeleton |
| Mentel M, Ionescu AE, (...), Szedlacsek SE | Scientific Reports | 2018 | | |
| RIM-Binding Protein 2 Promotes a Large Number of CaV1.3 Ca2+-Channels and Contributes to Fast Synaptic Vesicle Replenishment at Hair Cell Active Zones |
| Krinner S, Butola T, Jung S, Wichmann C, Moser T | Frontiers in Cellular Neuroscience | 2017 | | |
| Piccolo Promotes Vesicle Replenishment at a Fast Central Auditory Synapse |
| Butola T, Wichmann C, Moser T | Frontiers in Synaptic Neuroscience | 2017 | | |
10.1089/ars.2022.0076
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