| Property |
Value |
| Working Groups |
RG Wolf |
| Subproject |
C2 |
| Open Access |
Yes |
| Publication Type |
Journal Article |
| Peer Reviewed |
Yes |
| PMID |
40300603 |
| DOI |
10.1016/j.cell.2025.04.006 |
| Publication Year |
2025 |
| Title |
Alzheimer’s disease patient-derived high-molecular-weight tau impairs bursting in hippocampal neurons |
| Journal |
Cell |
| ISSN |
0092-8674 |
| eISSN |
1097-4172 |
| URL |
https://doi.org/10.1016/j.cell.2025.04.006 |
| Journal Abbreviation |
Cell |
| Authors |
Harris SS, Ellingford R, Hartmann J, Dasgupta D, Kehring M, Rajani RM, Graykowski D, Quittot N, Sivasankaran D, Commins C, Fan Z, Bond SA, Wolf F, Dupret D, Dolan RJ, Konnerth A, Neef A, Hyman BT, Busche MA |
| First Author |
Harris SS |
| Last Author |
Busche MA |
External Resources
cell.com...0408-8https://www.cell.com/action/showPdf?pii=S0092-8674%2825%2900408-8 Article fulltext
2/149170http://resolver.sub.uni-goettingen.de/purl?2/149170 GRO.publications identifier
9606https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 NCBI taxonomy (human, Homo sapiens)
10090https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090 NCBI taxonomy (mouse, Mus musculus)
0000-0001-6666-9485https://orcid.org/0000-0001-6666-9485 ORCID identifier (Samuel S. Harris)
0000-0002-6455-3013https://orcid.org/0000-0002-6455-3013 ORCID identifier (Robert Ellingford)
0000-0002-9093-301Xhttps://orcid.org/0000-0002-9093-301X ORCID identifier (Debanjan Dasgupta)
0009-0000-0517-2096https://orcid.org/0009-0000-0517-2096 ORCID identifier (Marten Kehring)
0000-0003-3391-8654https://orcid.org/0000-0003-3391-8654 ORCID identifier (Rikesh M. Rajani)
0000-0002-8004-2811https://orcid.org/0000-0002-8004-2811 ORCID identifier (David Graykowski)
0000-0003-1946-8677https://orcid.org/0000-0003-1946-8677 ORCID identifier (Noé Quittot)
0009-0001-6667-8987https://orcid.org/0009-0001-6667-8987 ORCID identifier (Dhanush Sivasankaran)
0000-0002-2963-335Xhttps://orcid.org/0000-0002-2963-335X ORCID identifier (Caitlin Commins)
0000-0001-9200-9739https://orcid.org/0000-0001-9200-9739 ORCID identifier (Suraya A. Bond)
0000-0002-7068-3762https://orcid.org/0000-0002-7068-3762 ORCID identifier (Fred Wolf)
0000-0002-0040-1766https://orcid.org/0000-0002-0040-1766 ORCID identifier (David Dupret)
0000-0002-9548-2676https://orcid.org/0000-0002-9548-2676 ORCID identifier (Arthur Konnerth)
0000-0003-4445-7478https://orcid.org/0000-0003-4445-7478 ORCID identifier (Andreas Neef)
0000-0002-7959-9401https://orcid.org/0000-0002-7959-9401 ORCID identifier (Bradley T. Hyman)
0000-0002-4416-7553https://orcid.org/0000-0002-4416-7553 ORCID identifier (Marc Aurel Busche)
1211https://prod.mbexc.uni-goettingen.de/literature/publications/1211 Published Data Registry entry (MBExC)
1/600https://mbexc.uni-goettingen.de/archive/1/600 Research Data Archive (supplemental material)
03vek6s52https://ror.org/03vek6s52 ROR identifier (03vek6s52, Harvard University)
002pd6e78https://ror.org/002pd6e78 ROR identifier (002pd6e78, Massachusetts General Hospital)
025z3z560https://ror.org/025z3z560 ROR identifier (025z3z560, Munich Cluster for Systems Neurology)
02kkvpp62https://ror.org/02kkvpp62 ROR identifier (02kkvpp62, Technical University of Munich)
02jx3x895https://ror.org/02jx3x895 ROR identifier (02jx3x895, University College London)
02s6k3f65https://ror.org/02s6k3f65 ROR identifier (02s6k3f65, University of Basel)
01nrxwf90https://ror.org/01nrxwf90 ROR identifier (01nrxwf90, University of Edinburgh)
01y9bpm73https://ror.org/01y9bpm73 ROR identifier (01y9bpm73, University of Göttingen)
052gg0110https://ror.org/052gg0110 ROR identifier (052gg0110, University of Oxford)
IMSR_JAX:007004https://scicrunch.org/resolver/IMSR_JAX:007004 SciCrunch identifier (RRID:IMSR_JAX:007004, B6.Cg-Tg(Camk2a-tTA)1Mmay/DboJ)
IMSR_JAX:008169https://scicrunch.org/resolver/IMSR_JAX:008169 SciCrunch identifier (RRID:IMSR_JAX:008169, B6;C3-Tg(Prnp-MAPT*P301S)PS19Vle/J)
IMSR_JAX:015815https://scicrunch.org/resolver/IMSR_JAX:015815 SciCrunch identifier (RRID:IMSR_JAX:015815, FVB-Fgf14Tg(tetO-MAPT*P301L)4510Kha/JlwsJ)
MMRRC_034832-JAXhttps://scicrunch.org/resolver/MMRRC_034832-JAX SciCrunch identifier (RRID:MMRRC_034832-JAX, B6.Cg-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax)
SCR_016422https://scicrunch.org/resolver/SCR_016422 SciCrunch identifier (RRID:SCR_016422, KiloSort)
SCR_000325https://scicrunch.org/resolver/SCR_000325 SciCrunch identifier (RRID:SCR_000325, IGOR Pro)
SCR_003070https://scicrunch.org/resolver/SCR_003070 SciCrunch identifier (RRID:SCR_003070, ImageJ)
SCR_001622https://scicrunch.org/resolver/SCR_001622 SciCrunch identifier (RRID:SCR_001622, MATLAB)
SCR_000034https://scicrunch.org/resolver/SCR_000034 SciCrunch identifier (RRID:SCR_000034, Patchmaster)
SCR_011323https://scicrunch.org/resolver/SCR_011323 SciCrunch identifier (RRID:SCR_011323, pClamp)
ars.els-...c1.pdfhttps://ars.els-cdn.com/content/image/1-s2.0-S0092867425004088-mmc1.pdf Supplemental material
billkarsh.github.io/SpikeGLX/https://billkarsh.github.io/SpikeGLX/ Supplemental material (code, reused)
github.com/cortex-lab/phyhttps://github.com/cortex-lab/phy Supplemental material (code, reused)
github.c...plorerhttps://github.com/petersaj/neuropixels_trajectory_explorer Supplemental material (code, reused)
github.c...x_v2.mhttps://github.com/tortlab/phase-amplitude-coupling/blob/master/ModIndex_v2.m Supplemental material (code, reused)
10.5281/zenodo.15044305https://doi.org/10.5281/zenodo.15044305 Zenodo identifier (10.5281/zenodo.15044305)
10.5281/zenodo.15044381https://doi.org/10.5281/zenodo.15044381 Zenodo identifier (10.5281/zenodo.15044381)
Linked Antibodies
| PID |
AG |
Type |
Antigen symbol |
Antibody Registry ID |
Name |
| primary-0157 |
 |
primary |
GAPDH |
AB_561053 |
GAPDH (14C10) Rabbit mAb |
| primary-0239 |
|
primary |
TAU |
AB_10013724 |
Polyclonal Rabbit Anti-Human Tau |
| primary-0240 |
|
primary |
MAPT |
AB_2314654 |
Tau Monoclonal Antibody |
| primary-0241 |
|
primary |
RBFOX3 |
AB_2298772 |
Anti-NeuN Antibody |
| primary-0242 |
|
primary |
TAU |
AB_2565341 |
Anti-Tau, 15-25 Antibody |
| primary-0243 |
|
primary |
GluN1 |
AB_2112011 |
GluN1 antibody |
| primary-0244 |
|
primary |
CACNA1E |
AB_2880808 |
CACNA1E Polyklonaler Antikörper |
| secondary-0245 |
|
secondary |
|
AB_621847 |
IRDye® 800CW Donkey anti-Mouse IgG Secondary Antibody |
| secondary-0246 |
|
secondary |
|
AB_621848 |
IRDye® 800CW Donkey anti-Rabbit IgG Secondary Antibody |
| secondary-0247 |
|
secondary |
|
AB_2535813 |
Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor 647 |
| secondary-0248 |
|
secondary |
|
AB_2534073 |
Goat anti-Mouse IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 594 |
| secondary-0249 |
|
secondary |
|
AB_2534079 |
Goat anti-Rabbit IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor™ 594 |
| secondary-0250 |
|
secondary |
|
AB_2535804 |
Goat anti-Mouse IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor™ 647 |