| Antigen symbol |
SNAP25 |
| Antibody Registry ID(s) |
AB_887790 |
| Name |
SNAP 25 |
| Alternative name |
synaptosome-associated protein 25 |
| Lab ID |
|
| Tag / Fluorophore |
|
| Raised in |
|
| Reacts with |
human, rat, mouse, hamster, chicken, goldfish |
| Clone |
|
| Isotype |
|
| Clonality |
polyclonal |
| Demasking |
unknown |
| Antigen |
Synthetic peptide corresponding to AA 192 to 206 from human SNAP25 |
| Crafted By |
company |
| Company / Manufacturer |
Synaptic Systems |
| Catalog no. |
111 002 |
| Lot no. |
|
| Description |
WB: 1 : 10000 (AP staining)
IP: yes
ICC: 1 : 500
IHC: 1 : 200
IHC-P/FFPE: 1 : 500
ELISA: yes (see remarks) |
| Localization |
SNAP 25 (synaptosome-associated protein of 25 kDa) is a highly conserved protein anchored to thecytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP 25 is thetarget of Botulinum neurotoxin A and E which cleave off 9 and 26 amino acids, respectively, from theC-terminus. SNAP 25 is part of the exocytotic fusion complex (v-SNARE) of neurons where it assembles withsyntaxin 1 and synaptobrevin. It is abundantly localized on the neuronal plasmalemma and onrecycling vesicles including synaptic vesicles. It is also expressed in neuroendocrine cells. There aretwo splice-variants, SNAP 25A and 25B. |
| Storage instruction |
|
| Receipt date |
2019-01-01 00:00:00 |
| Preparation date |
2019-03-04 00:00:00 |
| Created by |
|
| Last modified |
|